Comparison of Different Methods for Intra- and Postoperative Pain Therapy in Thoracic Surgery
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Thoracic Surgery
- Sponsor
- University Hospital, Bonn
- Enrollment
- 118
- Locations
- 2
- Primary Endpoint
- Opiate consumption
- Status
- Recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
The aim of the study is to determine which regional anaesthesiological technique (thoracic epidural analgesia or paravertebral block) is more suitable for thoracic surgery
Detailed Description
Thoracic interventions (lung operations) are associated with considerable postoperative pain, whereby an open surgical procedure via a skin incision (thoracotomy) is more painful than a minimally invasive endoscopic intervention (thoracoscopy). In order to reduce pain, a regional anaesthetic is administered during the induction of anaesthesia, which reduces pain both intraoperatively and postoperatively. In thoracic surgery, thoracic epidural analgesia (PDA) and paravertebral block (PVB) are the main regional anaesthesiological measures used, although it is unclear which of the two procedures is superior in terms of efficiency and effectiveness. Particularly intraoperatively, but also to some extent postoperatively, regional anaesthesia alone is usually not sufficient for pain management. Rather, additional systemic (i.e. intravenous) analgesics (especially opioids) are administered. Therefore, the amount of these additionally administered analgesics is a measure of the efficiency of the regional anaesthesia procedure.
Investigators
Martin Soehle
Vice Head of Department
University Hospital, Bonn
Eligibility Criteria
Inclusion Criteria
- •elective thoracic surgery
- •American Society of Anaesthesiologists (ASA) 1-3 status
- •written informed consent
Exclusion Criteria
- •pregnancy
- •adipositas (bmi \> 30)
- •cardiac arrhythmia
- •coagulation abnormalities
- •chronic pain
- •opiate abuses
Outcomes
Primary Outcomes
Opiate consumption
Time Frame: intraoperative
intraoperative opiate consumption
Secondary Outcomes
- postoperative pain(up to day 2 after surgery)
- anaesthetic depth(intraoperative)
- intraoperative nociception(intraoperative)
- Patient recovery(at day 1 after surgery)
- Patient satisfaction(at day 2 after surgery)
- pain score(from admission to post-anaesthesia care unit (PACU) until discharge from PACU (up to 1 hour after admission))