To study that whether giving oral contraceptives regularly to sheehans patients increases their bone strength
Not Applicable
- Conditions
- Health Condition 1: null- Patient had multiple hormone deficiencies, developed after post partum period due to pituitary necrosis
- Registration Number
- CTRI/2016/04/006786
- Lead Sponsor
- SGPGIMS
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Closed to Recruitment of Participants
- Sex
- Not specified
- Target Recruitment
- 30
Inclusion Criteria
1.Absent lactation and/or PPH (postpartum
hemorrage)and Menstrual disturbances after last delivery
2. Clinical evidence of deficiency of one or more pituitary hormones
3. Documentation of deficiency of at least one pituitary hormone
4. Absence of clinical or radiological feature of pituitary mass lesion
Exclusion Criteria
1. Other etiologies of hypopituitarism
2. Age > 42 years
3. Patients with chronic diseases like
uncontrolled diabetes, CAD, CKD, Liver disease and chronic inflammatory disorders
4. Patient with history of thromboembolic disorders
5. Patients with suspected breast, endometrial or cervical cancer
6. Patients on supra-physiological doses of steroids, anti-epileptic drugs and bisphosphonates
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To study the effect on BMD after sex steroid replacement in the follow up patients of Sheehans syndrome <br/ ><br>Timepoint: 1 year follow up <br/ ><br>
- Secondary Outcome Measures
Name Time Method morbidity <br/ ><br>fracture incidenceTimepoint: 1 year follow up