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临床试验/NCT01978678
NCT01978678已完成不适用

Does Asthma Phenotype Have Impact on Disease Control - Can Detection of Inflammation and Hyper Responsiveness Ensure Stable Disease Faster

Bispebjerg Hospital2 个研究点 分布在 1 个国家目标入组 80 人开始时间: 2012年11月最近更新:
适应症
干预措施
相关药物

试验速览

阶段
不适用
状态
已完成
入组人数
80
试验地点
2
主要终点
Control of asthma based on an algorithm

研究概览

简要总结

The application of biomarkers that are more closely associated with eosinophillic airway inflammation, such as measurements of FeNO level, cell count in induced sputum or bronchial reactivity could improve asthma control by better directing treatment. A systematic review and meta-analysis is to be conducted to assess the efficacy of tailoring asthma intervention on clinical symptoms compared with exhaled nitric oxide or induced sputum count.

详细描述

AHR used as outcome

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
15 Years 至 100 Years(Child, Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • positiv mannitol
  • asthma diagnose

排除标准

  • other lung disease

研究组 & 干预措施

Pulmicort

ICS and LABA - based on ACQ and FeNO

干预措施: Pulmicort (Drug)

结局指标

主要结局

Control of asthma based on an algorithm

时间窗: 2 years

Based on ACQ and FeNO

次要结局

  • The use of NO and sputum cell count as a marker in asthma management(2 years)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Vibeke Backer

DmSci, professor, md

Bispebjerg Hospital

研究点 (2)

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