NCT01978678已完成不适用
Does Asthma Phenotype Have Impact on Disease Control - Can Detection of Inflammation and Hyper Responsiveness Ensure Stable Disease Faster
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 80
- 试验地点
- 2
- 主要终点
- Control of asthma based on an algorithm
研究概览
简要总结
The application of biomarkers that are more closely associated with eosinophillic airway inflammation, such as measurements of FeNO level, cell count in induced sputum or bronchial reactivity could improve asthma control by better directing treatment. A systematic review and meta-analysis is to be conducted to assess the efficacy of tailoring asthma intervention on clinical symptoms compared with exhaled nitric oxide or induced sputum count.
详细描述
AHR used as outcome
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 15 Years 至 100 Years(Child, Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •positiv mannitol
- •asthma diagnose
排除标准
- •other lung disease
研究组 & 干预措施
Pulmicort
ICS and LABA - based on ACQ and FeNO
干预措施: Pulmicort (Drug)
结局指标
主要结局
Control of asthma based on an algorithm
时间窗: 2 years
Based on ACQ and FeNO
次要结局
- The use of NO and sputum cell count as a marker in asthma management(2 years)
研究者
Vibeke Backer
DmSci, professor, md
Bispebjerg Hospital
研究点 (2)
Loading locations...
相似试验
已完成
不适用
BIOmarkers in Severe AsthMa Patients on Omalizumab TreatmentSevere AsthmaNCT03361111Medical University of Warsaw16
Unknown
不适用
Airway Inflammation and Disease Burden in Asthmatic SmokersAsthmaNCT02833727Université de Montréal160
进行中(未招募)
1 期
Does asthma phenotype have impact on disease controlAsthmaMedDRA version: 16.1Level: PTClassification code 10003553Term: AsthmaSystem Organ Class: 10038738 - Respiratory, thoracic and mediastinal disordersEUCTR2013-004905-15-DKRespiratory Research Unit, Bispebjerg Hospital45
Unknown
不适用
Novel Inflammatory Markers in Different Phenotypes of Severe AsthmaNasal PolypsAsthmaNCT04888910University of Pisa80
已完成
不适用
Intense Airway Eosinophilia in AsthmaEosinophilic AsthmaAsthmaNCT03696914Laval University918
