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临床试验/NCT01978678
NCT01978678
已完成
不适用

Does Asthma Phenotype Have Impact on Disease Control - Can Detection of Inflammation and Hyper Responsiveness Ensure Stable Disease Faster

Bispebjerg Hospital2 个研究点 分布在 1 个国家目标入组 80 人2012年11月
适应症Asthma
干预措施Pulmicort
相关药物Pulmicort

概览

阶段
不适用
干预措施
Pulmicort
疾病 / 适应症
Asthma
发起方
Bispebjerg Hospital
入组人数
80
试验地点
2
主要终点
Control of asthma based on an algorithm
状态
已完成
最后更新
6年前

概览

简要总结

The application of biomarkers that are more closely associated with eosinophillic airway inflammation, such as measurements of FeNO level, cell count in induced sputum or bronchial reactivity could improve asthma control by better directing treatment. A systematic review and meta-analysis is to be conducted to assess the efficacy of tailoring asthma intervention on clinical symptoms compared with exhaled nitric oxide or induced sputum count.

详细描述

AHR used as outcome

注册库
clinicaltrials.gov
开始日期
2012年11月
结束日期
2015年1月
最后更新
6年前
研究类型
Observational
性别
All

研究者

责任方
Principal Investigator
主要研究者

Vibeke Backer

DmSci, professor, md

Bispebjerg Hospital

入排标准

入选标准

  • positiv mannitol
  • asthma diagnose

排除标准

  • other lung disease

研究组 & 干预措施

Pulmicort

ICS and LABA - based on ACQ and FeNO

干预措施: Pulmicort

结局指标

主要结局

Control of asthma based on an algorithm

时间窗: 2 years

Based on ACQ and FeNO

次要结局

  • The use of NO and sputum cell count as a marker in asthma management(2 years)

研究点 (2)

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