Een gerandomiseerde placebo gecontroleerde studie naar de toegevoegde waarde van D-cycloserine aan exposure therapie bij patiënten met een poststraumatische stress stoornis

GGZ Nijmegen0 个研究点开始时间: 2007年11月23日最近更新: 2014年1月27日

试验速览

暂无简介。

•Inclusion criteria are (1) age between 18 and 65 and (2) current DSM-IV diagnosis of PTSD established with a structured diagnostic interview (M.I.N.I. and CAPS).
•Are the trial subjects under 18? no
•Number of subjects for this age range:
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range
•F.1.3 Elderly (>=65 years) no
•F.1.3.1 Number of subjects for this age range

•Diagnostic exclusion criteria are (1) psychosis or delusion disorders (current or in the past) (2) suicidality (3) mental retardation (4) substance abuse or dependence or alcohol abuse of dependence, as established by a structured diagnostic interview (M.I.N.I.). Medical exclusion criteria are (1) pregnant or lactating women. Also women who are planning a pregnancy and don’t want to postpone a pregnancy during the treatment phase are excluded. According to the Informatorium Medicamentorum (2006), the influence of the use of D-cycloserine during pregnancy and breastfeeding is unknown. However, for safety reasons, we exclude these women. (2) patients who have a serious and unstable medical illness, as confirmed by their doctor, such as use of a pacemaker, renal disease or porfyrie (3) a history of epileptic seizures (4) medication use that may interfere with D-cycloserine, such as anticoagulants (5) patients who use antidepressants

发起方

GGZ Nijmegen