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临床试验/NCT03536169
NCT03536169已完成不适用

Utilization of Anti-reflux Treatment and Course of Illness Leading to Reoperation After Anti-reflux Surgery in a National Population-based Cohort

University of Southern Denmark1 个研究点 分布在 1 个国家目标入组 3,717 人开始时间: 2018年6月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
3,717
试验地点
1
主要终点
Rate of pharmacological anti-reflux treatment

研究概览

简要总结

The purpose of this study is to investigate course of illness leading to reoperation after primary anti-reflux surgery and investigate the utilization of anti-reflux treatment, both medical and surgical, in the period 2000-2017

详细描述

Aim The purpose of this study is to investigate course of illness leading to reoperation after primary anti-reflux surgery and investigate the utilization of anti-reflux treatment, both medical and surgical, in the period 2000-2017

Methods The study is a two-part register-based cohort study based on data from The National Patient Registry, The Civic Registry and Danish Anaesthesia Database in the period 1996-2017. The two individual parts of the study concerns the same population.

The population is defined as all adult Danish patients undergoing anti-reflux surgery (Nomesco: KJBC00, KJBC01, KJBC02, KJBW96, KJBW97) from 2000-2017 identified from The National Patient Register.

Age, sex, Charlson Comorbidity Index at date of surgery and length of stay in relation to any surgery and any surgical or endoscopic procedure performed after anti-reflux surgery (including diagnosis 30 days postoperatively to establish possible morbidity) are derived from the National Patient Registry.

ASA-score, weight, height, use of alcohol or tobacco and priority of any surgery (emergency or planned) during the study period are retrieved from The Danish Anaesthesia Database. From the Civic Register, data on mortality in the study period are retrieved.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • All adult Danish patients undergoing anti-reflux surgery (Nomesco: KJBC00, KJBC01, KJBC02, KJBW96, KJBW97) from 2000-2017 identified from The National Patient Register.

排除标准

  • Any diagnosis of gastrointestinal cancer during the study period

结局指标

主要结局

Rate of pharmacological anti-reflux treatment

时间窗: 2000-2017

Based on Danish census-data

Reoperation

时间窗: 2000-2017 (Maximum of 17 years follow-up, minimum of 1 year)

Any reoperative anti-reflux surgery

Rate of anti-reflux surgery

时间窗: 2000-2017

Based on Danish census-data

次要结局

  • Emergency reoperative anti-reflux surgery(2000-2017(Maximum of 17 years follow-up, minimum of 1 year))

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Jonas Sanberg Jensen

MD, Ph.d.-student

University of Southern Denmark

研究点 (1)

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