Utilization of Anti-reflux Treatment and Course of Illness Leading to Reoperation After Anti-reflux Surgery in a National Population-based Cohort
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 3,717
- 试验地点
- 1
- 主要终点
- Rate of pharmacological anti-reflux treatment
研究概览
简要总结
The purpose of this study is to investigate course of illness leading to reoperation after primary anti-reflux surgery and investigate the utilization of anti-reflux treatment, both medical and surgical, in the period 2000-2017
详细描述
Aim The purpose of this study is to investigate course of illness leading to reoperation after primary anti-reflux surgery and investigate the utilization of anti-reflux treatment, both medical and surgical, in the period 2000-2017
Methods The study is a two-part register-based cohort study based on data from The National Patient Registry, The Civic Registry and Danish Anaesthesia Database in the period 1996-2017. The two individual parts of the study concerns the same population.
The population is defined as all adult Danish patients undergoing anti-reflux surgery (Nomesco: KJBC00, KJBC01, KJBC02, KJBW96, KJBW97) from 2000-2017 identified from The National Patient Register.
Age, sex, Charlson Comorbidity Index at date of surgery and length of stay in relation to any surgery and any surgical or endoscopic procedure performed after anti-reflux surgery (including diagnosis 30 days postoperatively to establish possible morbidity) are derived from the National Patient Registry.
ASA-score, weight, height, use of alcohol or tobacco and priority of any surgery (emergency or planned) during the study period are retrieved from The Danish Anaesthesia Database. From the Civic Register, data on mortality in the study period are retrieved.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All adult Danish patients undergoing anti-reflux surgery (Nomesco: KJBC00, KJBC01, KJBC02, KJBW96, KJBW97) from 2000-2017 identified from The National Patient Register.
排除标准
- •Any diagnosis of gastrointestinal cancer during the study period
结局指标
主要结局
Rate of pharmacological anti-reflux treatment
时间窗: 2000-2017
Based on Danish census-data
Reoperation
时间窗: 2000-2017 (Maximum of 17 years follow-up, minimum of 1 year)
Any reoperative anti-reflux surgery
Rate of anti-reflux surgery
时间窗: 2000-2017
Based on Danish census-data
次要结局
- Emergency reoperative anti-reflux surgery(2000-2017(Maximum of 17 years follow-up, minimum of 1 year))
研究者
Jonas Sanberg Jensen
MD, Ph.d.-student
University of Southern Denmark
