MedPath

EFFICACY OF RUESI DADTON ON MILD COGNITIVE IMPAIRMENT: A RANDOMIZED CONTROL TRIA

Phase 3
Completed
Conditions
mild cognitive impairmentelderly
mild cognitive impairment
elderly
Thai exercise
Ruesi Dadton
BDNF
irisin
oxidative stress
mind body medicine
Registration Number
TCTR20200727001
Lead Sponsor
-
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
All
Target Recruitment
71
Inclusion Criteria

Age between 50-80 year
- Ability to read write hearing, speaking and communication in Thai language
- Body mass index at low to moderate risk (19 - 27.5 kg/m2)
- Complaint cognition more than normal in the same age or compare with the past
- MMSE scores less than 24 points
- MoCA) scores less than 26 points
- Diagnosed from neurologist that amnestic-MCI

Exclusion Criteria

- Diagnosed with dementia
- History or diagnosis with cardiovascular disease
- Neurological disease or mental symptoms
- Blood pressure more than 160/100 mmHg
- History of alcoholism or drugs addiction
- Spine problems such as scoliosis, spine trauma, and disc herniation
- Knee pain (VAS at least 8)
- Cannot sit in a cross position
- Severe accidents in the prior 3 months
- History of brain accident or brain injury
- Continue regular exercise within the prior 2 years ( 30 min/day or over, 3 days/week or over)
- Intent to exercise that related to Ruesi Dadton, Tai Chi, Yoga, or Chi-Qong within three months

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
cognitive functions 12 weeks MoCA, MMSE,cognitive functions 12 weeks MMSE,BDNF 12 weeks blood serum,irisin 12 weeks blood serum,oxidative stress 12 weeks urine ,balance 12 weeks single leg standing,frialty 12 weeks grip strength
Secondary Outcome Measures
NameTimeMethod
cognitive function 12 weeks verbal fluency test,cognitive function 12 weeks Trial making part A, B, B-A
© Copyright 2025. All Rights Reserved by MedPath