Clitoral Location in Relation to Sexual Function Using Pelvic MRI: A Case-Control Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 35
- 试验地点
- 1
- 主要终点
- Clitoral Measurements Using Pelvic MRI
研究概览
简要总结
Women who are unable to achieve orgasm compared to women who have normal orgasmic function may have different clitoral anatomy and different hormone levels. The investigators hypothesis is that women who have difficulty with orgasm may have a clitoris that is closer to the vagina and may have higher testosterone levels. Pelvic MRI will be used to observe whether clitoral measurements differ between women with normal orgasmic function vs. those with anorgasmia.
详细描述
Women unable with anorgasmia and those with normal orgasmic function will undergo pelvic MRI so that clitoral measurements can be taken and then compared for differences.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 55 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •Premenopausal female aged 18-55 years
- •Sexually active (at least 1 heterosexual partner in the past 4 weeks)
- •Cases must have difficulty with orgasm or be anorgasmic
- •Controls must have normal sexual function
排除标准
- •Not sexually active
- •Homosexual orientation
- •Postmenopausal
- •Stage >2 pelvic organ prolapse (POP-Q measurements beyond hymen)
- •Urinary incontinence with coitus limiting sexual activity
- •Severe vaginal atrophy
- •Pelvic pain/dyspareunia (
- •Currently pregnant
- •Depression being treated with SSRIs (depression alone or treatment of depression with non-SSRI medications is not an exclusion)
- •Currently taking testosterone supplements
- •History of sexual abuse
- •Large pelvic mass (benign or cancerous) impeding MRI measurements or grossly abnormal pelvic anatomy.
结局指标
主要结局
Clitoral Measurements Using Pelvic MRI
时间窗: Between day 1-14 (follicular phase) of menstrual cycle
All cases and controls will undergo a pelvic MRI without contrast to assess the clitoral complex.
次要结局
- Total Testosterone(Between day 1-14 (follicular phase) of menstrual cycle)
- Free Testosterone(Between day 1-14 (follicular phase) of menstrual cycle)
- Free Androgen Index(Between day 1-14 (follicular phase) of menstrual cycle)
- FSFI Arousal(baseline visit)
- FSFI Desire(baseline visit)
- Female Sexual Function Index (FSFI) Total Score(baseline visit)
- FSFI Orgasm(baseline visit)
- FSFI Lubrication(baseline visit)
- FSFI Satisfaction(baseline visit)
- FSFI Pain(baseline visit)