Perifollicular Doppler in Natural Cycle In Vitro Fertilization
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Enrollment
- 160
- Locations
- 1
- Primary Endpoint
- Quality perifollicular doppler and quality of the oocyte
Study Overview
Brief Summary
Perifollicular Doppler could reflect the quality of the follicle's vascularization and, consequently, the one of the oocyte that ensues from it. Perifollicuar Doppler is the analysis, in ultrasound, of the blood flow in vessels surrounding the follicle.
The goal of this study is to evaluate if there is a link, in natural cycle In Vitro Fertilization, between the quality of the vascularization and the one of the oocyte, the embryo and the pregnancy.
Study Design
- Study Type
- Observational
- Observational Model
- Case Only
- Time Perspective
- Prospective
Eligibility Criteria
- Ages
- 18 Years to 38 Years (Adult)
- Sex
- Female
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Patient with a natural In Vitro Fertilization cycle.
- •Patient under 38 years old
- •Body mass indice under 35
- •Ovulatory cycles between 20-35 days
Exclusion Criteria
- •Patient with a stimulation In Vitro Fertilization cycle
- •Patient with a naturalIn Vitro Fertilization cycle with egg donor
- •Patient with a natural In Vitro Fertilization cycle with freezing embryo
- •Smoking patient
- •Diabetic patient
- •Patient with treatment of antihypertensive drug, anticoagulant, antiplatelet, vasodilator
- •Body mass indice over 35
- •Patient over 38 years old
- •Patient without ovulation or cycle over 35 days
- •Percutaneous Epididymal Sperm Aspiration (PESA), Testicular Sperm Extraction (TESE) or micro TESE
Outcomes
Primary Outcomes
Quality perifollicular doppler and quality of the oocyte
Time Frame: 2 weeks
The measurements are done twice; on days of induction and oocyte retrieval. During the blood sample collection on the day of the induction, there is also a measurement of progesterone, estradiol and luteinizing hormone (LH).
Secondary Outcomes
No secondary outcomes reported