De beoordeling van de effectiviteit van twee probiotica bij het in stand houden van de mondgezondheid: een praktijkonderzoek.
Completed
- Conditions
- Experimental gingivitis modelProbioticsBleeding on marginal probingMicrobiomeOral healthProbioticaMondgezondheidTandvleesontsteking
- Registration Number
- NL-OMON25529
- Lead Sponsor
- Ir. W. Th. FokkemaACTA Dental Research B.V. (ADR)Gustav Mahlerlaan 30041081 LA Amsterdam, NLw.fokkema@acta.nl / +31 6 28 724 788
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 117
Inclusion Criteria
1.Willing and able to give written informed consent and willing and able to comply to all study procedures;
2.Adult, ≥ 18 years - 55 years;
Exclusion Criteria
1.Not meeting the inclusion criteria;
2.ACTA dental student or ACTA employee;
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Bleeding on marginal probing
- Secondary Outcome Measures
Name Time Method Microbiome composition
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms do oral probiotic strains use to modulate gingival microbiome in experimental gingivitis models?
How effective are probiotics compared to standard-of-care treatments for maintaining oral health in patients with experimental gingivitis?
Which biomarkers correlate with response to probiotic interventions in the context of marginal bleeding and microbiome changes?
What are the potential adverse events associated with long-term use of oral probiotics in clinical practice for gingival health?
Are there synergistic effects when combining the tested probiotics with other oral health compounds like chlorhexidine or prebiotics?