CTRI/2023/08/056196
Recruiting
未知
Effects of SGLT2 inhibitors on cardiac remodelling in patients with atrial fibrillation and left ventricular systolic dysfunction- An observational study - NI
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- Health Condition 1: I482- Chronic atrial fibrillationHealth Condition 2: I501- Left ventricular failure, unspecified
- Sponsor
- Kasturba Medical College
- Status
- Recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •a)All patients with non\-valvular AF with LV systolic dysfunction (LVEF \<50%) b)Coronary artery disease (Both revascularized and non\-revascularized) with AF and LV systolic dysfunction.
Exclusion Criteria
- •a)Valvular AF b)Severe systemic infection c)Serious liver or renal dysfunction (estimated glomerular filtration rate \<30 mL/min/1\.73 m2\) d)Pregnant or breastfeeding, or planning to conceive in the study period (female patients only) e)Dehydration (abnormal hematocrit and blood urea nitrogen, symptoms of dehydration) f)Urinary tract or genital infection g)History of hypersensitivity to the study drug h)History of severe ketosis, diabetic coma or precoma i)Any other contraindication to SGLT2 inhibitor j)ICD or coronary revascularization after enrolment into the study
Outcomes
Primary Outcomes
Not specified
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