The effect of cholesterom mouthwash on oral care and prevention of late-onset sepsis

Not Applicable

Recruiting

Conditions: Condition 1: Oral care of preterm infant. Condition 2: sepsis.
Encounter for health supervision and care of other healthy infant and child
Bacterial sepsis of newborn
Z76.2

Registration Number: IRCT20200818048448N1

Lead Sponsor: Tabriz University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: All

Target Recruitment: 70

Inclusion Criteria

Premature infants between 28 and 32 weeks of pregnancy
Being hospitalized in level one and two neonatal intensive care units for to 5 days
Access to the mother's colostrum
No abnormalities in the infant's mouth and throat
The mother does not have active viral infections during pregnancy and delivery
Infants under nasal cpap
Being NPO

Exclusion Criteria

Neonatal asphyxia (umbilical cord pH <0.7)
Disorders during infant birth
Chromosomal abnormalities
Development of early neonatal sepsis
Unstability of the infant's physiological condition more than twice before the intervention (decreased O2 saturation, bradycardia, etc.)
Receiving mechanical ventilation
Using of certain medicene by the mother, which is prohibited during breastfeeding

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Oral care level. Timepoint: At the end of each day of the intervention (for 5 days). Method of measurement: To assess the level of oral care of the infant, the Oral Assessment Tool for Neonates will be used, in which the infant's mouth is examined in four parts of the lips and corners of the mouth, tongue, saliva and mucous membranes. The status of each section is scored from 1 to 3. Therefore, the level of need for oral care will be between zero and 12, and as the score increases, the level of oral care for the infant will also increase.;Late-onset sepsis. Timepoint: 72 hours after birth. Method of measurement: The initial diagnosis of sepsis is based on clinical symptoms (fever, poor feeding, respiratory distress, hypotension, decreased reflexes, etc.) and if symptoms are present, it will be confirmed by laboratory CBC values and positive CRP and blood culture.

Secondary Outcome Measures