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Clinical Trials/NCT03716817
NCT03716817
Completed
Not Applicable

Clinical Evaluation of Chairside CAD/CAM Resilient Ceramic Crowns

University of Michigan2 sites in 1 country50 target enrollmentOctober 1, 2018

Overview

Phase
Not Applicable
Intervention
Tetric CAD
Conditions
Fractured Tooth
Sponsor
University of Michigan
Enrollment
50
Locations
2
Primary Endpoint
Crown failure
Status
Completed
Last Updated
4 days ago

Overview

Brief Summary

This investigation will be a clinical trial to study the performance of a new resin-based ceramic material for crowns. The material has been approved by the FDA for patient treatment. A computer technique will be used to fabricate the crowns in a single appointment without the need for a temporary crown or second appointment. The purpose of the study is to measure how well the high strength crowns function over an extended period of time.

Detailed Description

The study will be composed of 50 crowns placed in adult patients that have been identified as requiring at least one crown on a posterior tooth. A maximum of two crowns per patient will be completed. All the crowns will be made from the same resilient ceramic CAD/CAM block(Tetric CAD/Ivoclar Vivadent). The crowns are placed using an adhesive bonding process including a total etch process with a universal adhesive (Adhese by Ivoclar Vivadent) and dual-cured resin cement (Variolink Esthetic by Ivoclar Vivadent). The crowns are planned to be evaluated at 6 months, 1 year, 2 years, 3 years, and if funding permits, 4 years, and 5 years. At each appointment, an examination of the crown will be completed as well as clinical photographs, an intraoral digital scan, and impression of the crown.

Registry
clinicaltrials.gov
Start Date
October 1, 2018
End Date
June 18, 2024
Last Updated
4 days ago
Study Type
Interventional
Study Design
Single Group
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Dennis J. Fasbinder, DDS

Clinica Professor

University of Michigan

Eligibility Criteria

Inclusion Criteria

  • must have at least one carious lesion or defective restoration or fractured tooth in a molar or premolar
  • reason for restoration should extend more than one-half the intercuspal width of the tooth requiring a full crown restoration
  • Teeth to be vital and asymptomatic prior to treatment
  • No more than two restorations will be placed per patient. If a patient presents with more than two acceptable teeth for the study, molar teeth will be included prior to premolar teeth.

Exclusion Criteria

  • Devital or sensitive teeth
  • Teeth with prior endodontic treatment of any kind
  • Teeth with a history of direct or indirect pulp capping procedures
  • Patients with significant untreated dental disease to include periodontitis and rampant caries
  • Pregnant or lactating women
  • Patients with a history of allergies to any of the materials to be used in the study
  • Patients unable to return for the recall appointments

Arms & Interventions

Tetric CAD Crown

Tetri CAD crowns will hand polished and cemented with a dual cured resin cement (Variolink Esthetic by Ivoclar Vivadent).

Intervention: Tetric CAD

Outcomes

Primary Outcomes

Crown failure

Time Frame: from delivery of the crown up to 5 years

Crown failure includes fracture of the crown or loss of the crown requiring placement of a new crown at any time between delivery and five years.

Crown Failure

Time Frame: from delivery of the crown up to 5 years

Crown failure includes fracture of the crown or loss of the crown requiring placement of a new crown at any time between delivery and five years.

Secondary Outcomes

  • Tooth sensitivity(from delivery of the crown up to 5 years)
  • Crown loss of retention(from delivery of the crown up to 5 years)
  • Margin staining(from delivery of the crown up to 5 years)
  • Crown Loss of Retention(from delivery of the crown up to 5 years)
  • Tooth Sensitivity(from delivery of the crown up to 5 years)
  • Margin Staining(from delivery of the crown up to 5 years)

Study Sites (2)

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