RELEASE: Redressing long-term antidepressant use in general practice

Not Applicable

Recruiting

• Conditions: ong-term antidepressant use; Long-term antidepressant use; Public Health - Health service research

• Registration Number: ACTRN12622001379707
• Lead Sponsor: The University of Queensland

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2022-10-27
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 590

Inclusion Criteria

18 years or older AND

Currently on antidepressant medication AND

On any combination of antidepressant medication with a total duration of longer than 12 months including selective serotonin reuptake inhibitors (SSRIs), serotonin–norepinephrine reuptake inhibitors (SNRIs) and other antidepressants including Mirtazapine, Vortioxetine, Mianserin, Moclobemide, Reboxetine, Agomelatine.

Exclusion Criteria

GP considers the patient not suitable for medication review (for example, recent personal crisis)

Bipolar disorder

History of psychotic or obsessive-compulsive disorder

Currently under care of a psychiatrist

Current substance use disorder

Non-psychiatric indication for antidepressant (for example, neuropathic pain)

Dementia or unable to give informed consent

Not on antidepressants

Not on antidepressants for longer than 12 months

Aged care residents

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Antidepressant discontinuation self-reported by patients via study-specific online questionnaire. Discontinuation is defined as 0mg antidepressant maintained for at least 2 weeks. [ At 12 months post participant allocation]