Evaluation of the effects of the addition of atropine during propofol/remifentanil induction of anesthesia on hemodynamics, microvascular blood flow and tissue oxygenenation in patients undergoing ophthalmic surgery.
Completed
- Conditions
- inductie en de hemodynamiek bij oogoperatie waarbij algehele narcose nodig ishemodynamice and bloodpressure
- Registration Number
- NL-OMON37131
- Lead Sponsor
- anesthesiologie- onderzoeksbureau
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 60
Inclusion Criteria
Patients requiring general anaesthesia.
- Patient*s age >= 18 years and older.
- Patient and surgical procedure appropriate for treatment with either sufentanil or remifentanil.
Exclusion Criteria
- Patient*s refusal
- Patient*s age < 18 years
- Patients in which atropine is contra-indicated, such as severe aortic valve stenosis, hypertrophic cardiomyopathy or coronary artery disease
-pregnancy
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>The evolution of heart rate, arterial blood pressure, cardiac output, the<br /><br>peripheral tissue oxygenation (thenar) and cerebral oxygen saturation<br /><br>(forehead) and buccal microcirculation. </p><br>
- Secondary Outcome Measures
Name Time Method <p>Is the requirement of other vasoactive medication (norepinephrine) for<br /><br>hemodynamic control different between the two groups?</p><br>