INTRAOPERATIVE REAL TIME IMAGING WITH A DUAL RADIOACTIVE/FLUORESCENCE MODALITY FOR SENTINEL NODE LOCALIZATION. A FEASIBILITY STUDY INCLUDING REPRODUCIBILITY OF MULTIMODALITY LYMPHATIC MAPPING WITH A COCKTAIL TRACER CONTAINING 99mTc NANOCOLLOID /ICG
- Conditions
- malignancy10027655
- Registration Number
- NL-OMON33218
- Lead Sponsor
- Antoni van Leeuwenhoek Ziekenhuis
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 40
Inclusion Criteria
Patients presenting cutaneous melanoma of head/neck and upper part of the trunk
Patients presenting oral cavity malignances T1-2N0
Breast cancer patients with a medially located tumor (palpable tumors and non-palpable tumors detectable by ultrasound) with demonstrated drainage outside the axilla
Patients with clinical N0 stage
Exclusion Criteria
Evidence of regional or distant metastases
Non-palpable breast tumors requiring stereotaxis for tracer administration
Incapacity or unwillingness of participant to give written informed consent
Allergy to iodides
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>1.number and location of sentinel nodes after 99mTc-nanocolloid injection<br /><br>2.number and location of sentinel nodes after cocktail injection<br /><br>3.different locations and number of sentinel nodes after first injection<br /><br>4.surgical retrieval rate and procedure time</p><br>
- Secondary Outcome Measures
Name Time Method <p>None</p><br>