Effect of anesthesia information before surgery in neurosurgical patients.
Phase 2
Completed
- Conditions
- Health Condition 1: G969- Disorder of central nervous system, unspecified
- Registration Number
- CTRI/2022/06/043327
- Lead Sponsor
- AIIMS
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 50
Inclusion Criteria
1.Adult patients [18-65 years] undergoing 2-3 level thoracolumbar spinal fusion surgery
2.Written informed consent
3.American Society of Anesthesiologists class I&II
4.Age of >18 years
5.Either gender
6.Spine pathologies undergoing 2-3 level thoracolumbar spinal fusion surgery
7.Full Glasgow coma score (E4V5M6)
8.Estimated operative time of <= 6 hours and anesthesia time of <= 8 hours
Exclusion Criteria
1.Non consenting patient
2.Mini-Mental State Examination [MMSE] <24
3.Any history of previous brain surgery
4.Current or past history of any cardiac disease or medication
5.Any history of lung disease, liver or kidney dysfunction
6.Body mass index of > 35 kg/m2
7.Preoperative cognitive dysfunction
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1.Time to emergence [from discontinuation of anesthetics to eye opening on command in minutes] <br/ ><br>2.Extubation time [from discontinuation of anesthetics to tracheal extubation in minutes] <br/ ><br>Timepoint: At the end of surgery.
- Secondary Outcome Measures
Name Time Method 1.Postoperative delirium [assessed using CAM-ICU]Timepoint: 60 minutes after extubation;2.Postoperative early cognitive dysfunction [assessed using MMSE]Timepoint: 60 minutes after extubation;3.Patients satisfaction score [6-point Likert scale with a score ranging from 0 to 5]Timepoint: 60 minutes after extubation