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临床试验/NCT06643052
NCT06643052尚未招募不适用

Cahnge in Management of Suspected Early Onset Neonetal Sepsis After Assimilation of Early Onset Sepsis Calculator

Hillel Yaffe Medical Center1 个研究点 分布在 1 个国家目标入组 6,300 人开始时间: 2025年12月1日最近更新:
适应症

试验速览

阶段
不适用
状态
尚未招募
入组人数
6,300
试验地点
1
主要终点
Number of negative blood cultures out of all blood cultures

研究概览

简要总结

Early neonatal sepsis requires rapid and efficient intervention to prevent morbidity and mortality. Management of such a case includes invasive blood examinations, elongation of maternal and neonatal length of stay, and empiric antibiotic therapy. These actions has major side effects. On 2017, Kaiser-Permanente started using a calculator that weighs the chances for early onset neonatal sepsis, and states the best investigation and follow-up regimn for the specific newborn infant. Eversince, policy of managing neonatal suspected early onset sepsis has chaged globally, including in Israel. Current knowledge regarding the local outcome since the use of the calculatir is scarce.

The goal of the study is to evaluate the change in management of suspected neonatal early onset sepsis, including its economic value, between periods before and after assimilation of the calculator in Hillel Yaffe nedica l center.

详细描述

Early neonatal sepsis requires rapid and efficient intervention to prevent morbidity and mortality. Management of such a case includes invasive blood examinations, elongation of maternal and neonatal length of stay, and empiric antibiotic therapy. These actions has major side effects. On 2017, Kaiser-Permanente started using a calculator that weighs the chances for early onset neonatal sepsis, and states the best investigation and follow-up regimn for the specific newborn infant. Eversince, policy of managing neonatal suspected early onset sepsis has chaged globally, including in Israel. Current knowledge regarding the local outcome since the use of the calculatir is scarce.

The goal of the study is to evaluate the change in management of suspected neonatal early onset sepsis, including its economic value, between periods before and after assimilation of the calculator in Hillel Yaffe nedical center.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Retrospective

入排标准

年龄范围
— 至 7 Days(Child)
性别
All
接受健康志愿者

入选标准

  • Newborn unfants born in Hillel Yaffe medical center
  • 35 weeks of gestation or more
  • Blood culture was taken

排除标准

  • Sepsis workup for other reason
  • 34 weeks of gestation or less

结局指标

主要结局

Number of negative blood cultures out of all blood cultures

时间窗: during first week of life

Total count of negative blood cultures out of all blood cultures in all patients in group

Number of positive blood cultures

时间窗: during first week of life

Total count of positive blood cultures in all patients in group

次要结局

  • Cost of treatment(during first week of life)

研究者

申办方类型
Other Gov
责任方
Principal Investigator
主要研究者

Erez Nadir, MD

Neonatologist

Hillel Yaffe Medical Center

研究点 (1)

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