Cahnge in Management of Suspected Early Onset Neonetal Sepsis After Assimilation of Early Onset Sepsis Calculator
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 6,300
- 试验地点
- 1
- 主要终点
- Number of negative blood cultures out of all blood cultures
研究概览
简要总结
Early neonatal sepsis requires rapid and efficient intervention to prevent morbidity and mortality. Management of such a case includes invasive blood examinations, elongation of maternal and neonatal length of stay, and empiric antibiotic therapy. These actions has major side effects. On 2017, Kaiser-Permanente started using a calculator that weighs the chances for early onset neonatal sepsis, and states the best investigation and follow-up regimn for the specific newborn infant. Eversince, policy of managing neonatal suspected early onset sepsis has chaged globally, including in Israel. Current knowledge regarding the local outcome since the use of the calculatir is scarce.
The goal of the study is to evaluate the change in management of suspected neonatal early onset sepsis, including its economic value, between periods before and after assimilation of the calculator in Hillel Yaffe nedica l center.
详细描述
Early neonatal sepsis requires rapid and efficient intervention to prevent morbidity and mortality. Management of such a case includes invasive blood examinations, elongation of maternal and neonatal length of stay, and empiric antibiotic therapy. These actions has major side effects. On 2017, Kaiser-Permanente started using a calculator that weighs the chances for early onset neonatal sepsis, and states the best investigation and follow-up regimn for the specific newborn infant. Eversince, policy of managing neonatal suspected early onset sepsis has chaged globally, including in Israel. Current knowledge regarding the local outcome since the use of the calculatir is scarce.
The goal of the study is to evaluate the change in management of suspected neonatal early onset sepsis, including its economic value, between periods before and after assimilation of the calculator in Hillel Yaffe nedical center.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- — 至 7 Days(Child)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Newborn unfants born in Hillel Yaffe medical center
- •35 weeks of gestation or more
- •Blood culture was taken
排除标准
- •Sepsis workup for other reason
- •34 weeks of gestation or less
结局指标
主要结局
Number of negative blood cultures out of all blood cultures
时间窗: during first week of life
Total count of negative blood cultures out of all blood cultures in all patients in group
Number of positive blood cultures
时间窗: during first week of life
Total count of positive blood cultures in all patients in group
次要结局
- Cost of treatment(during first week of life)
研究者
Erez Nadir, MD
Neonatologist
Hillel Yaffe Medical Center
