Preliminary Research Using Artificial Intelligence Technology to Identify Differences in Facial Expressions Between Healthy People, Patients With Cognitive Decline, and Patients With Dementia

Recruiting

• Conditions: Artificial Intelligence Technology; Cognitive Decline; Identify; Dementia; Facial Expressions

• Registration Number: NCT06513403
• Lead Sponsor: National Taiwan University Hospital

Brief Summary

Through artificial intelligence technology, we have conducted a preliminary study aimed at identifying differences in facial expressions among healthy individuals, patients with cognitive decline, and dementia patients. This research offers a novel method and tool for dementia screening, contributing to effective strategies for dementia prevention in our country. By utilizing this approach, we can effectively delay the onset of disability, promote healthy aging among our elderly population, reduce the caregiving burden on individuals, families, and society, and lower medical expenses.

Detailed Description

Not available

Study Timeline

• Status Verified: 2024-07
• Study First Submitted: 2024-07-17
• Study First Submitted QC: 2024-07-17
• Study First Posted: 2024-07-22
• Study Start: 2024-09-01
• Last Update Submitted: 2025-04-10
• Last Update Posted: 2025-04-15
• Primary Completion: 2025-08-31
• Study Completion: 2025-10-31

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Age between 50 and 75 years.

• Experimental group:
• MCI group: CDR score of 0.5 or MMSE score between 20-25 (mild/early stage).
• Dementia group: CDR score greater than 1 or MMSE score between 10-19 (moderate/middle stage).
• Control group:
• Health group: MMSE score of 26 or above.
• Participants must be conscious and able to follow instructions.

Exclusion Criteria

Not provided

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Facial Expression Test	2024/8/1-2025/10/31	(A) Participants will sit in front of a computer screen and watch videos depicting positive (happy) or negative (sad) emotional stimuli. Each video will be less than 60 seconds long. (B) Participants will undergo the memory recall and calculation ability tests included in the MMSE. (C) While participants are undergoing the tests, video recording equipment will be used to observe and record the facial expression responses of the three groups.

Trial Locations

Locations (1)

NTUH; 🇨🇳 Hsinchu, Taiwan