NCT04598061Unknown不适用
IV Dexmedetomidine as Spinal Anesthesia Adjuvant in Infants : RACHI_dex
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 入组人数
- 210
- 试验地点
- 1
- 主要终点
- duration of motor block
研究概览
简要总结
- Spinal anesthesia in newborns is one of " Gold standard " techniques in short subumbilical surgeries (less than 30 minutes) with advantage of avoiding the risks inherent to general anesthesia.
- Spinal anesthesia of the newborn remains a complex technical procedure with a failure rate of up to 16%. The child's movements and certain degrees of discomfort may also interfere with the successful completion of the procedure.
- The second major issue of spinal anesthesia is the limitation of the motor block duration and the need for general anesthesia to complete the surgery
- Spinal anesthesia duration can be prolonged by the addition of differents adjuvant such as opioid or alpha 2 adrenergic agonist.
- Since 2018, dexmedetomidine, an alpha 2 adrenergic agonist with sedative, analgesic and anxiolytic properties, is being used as a current and standard practice in our anesthesia department. Intravenous administrationis performed ten to twenty minutes before spinal anesthesia placement in all children weighing less than 7 kg undergoing an infra-umbilical surgery of expected duration of less than 1 hour. This strategy ensures the child's comfort and allows the procedure to be performed under optimal conditions for practitionner.
- The objective of this study is to review our practices and to evaluate the impact of the use of dexmedetomidine during spinal anesthesia of newborns and infants.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- 未提供
研究组 & 干预措施
Newborns or Infants less than 7 kg undergoing an infra-umbilical surgery
Newborns or Infants less than 7 kg undergoing an infra-umbilical surgery
干预措施: Dexmedetomidine IV (Drug)
结局指标
主要结局
duration of motor block
时间窗: immediately after procedure in the recovery room
Time at which the motor block is finished
次要结局
未报告次要终点
研究者
研究点 (1)
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