Exploratory clinical study to evaluate the safety of Platelet rich plasma transplantation for the periodontal tissue defects - Platelet rich plasma transplantation for the periodontal tissue defects

Tobita Morikuni0 个研究点目标入组 2 人开始时间: 2020年3月31日最近更新: 2023年10月17日

试验速览

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•1) Have a Periodontal pocket more than 5 mm at baseline examination.
•2) Intrabony defect is 5 mm and more depth, and 2 mm and more width at interproximal site of the experimental tooth by X-ray examination.
•3) Already have received initial preparation at the screening.
•4) Mobility of experimental tooth is 0, 1, or 2, and exist keratinized gingiva.
•5) Persons whose oral hygiene is established Good oral hygiene.
•6) 20 years and older.
•7) Signed informed consent

•1) Can not be measured clinical attachment level of experimental tooth.
•2) Have a history of Complicate malignant tumor.
•3) Suspected of oral malignant tumor or precancerous lesion.
•4) Need to undergo the treatment, such as surgical treatment, restorative treatment or root canal treatment, at the experimental tooth within 36 weeks after transplant.
•5) Pregnancy, during breastfeeding, or possibility of pregnancy.
•6) Persons who suffer from disorders of kidney, liver or blood
•7) Have disease of kidney, liver and/or blood.
•8) Have active infectious diseases.
•9) Alcoholism or Drug dependence.
•10) Mental or consciousness disorder.
•11) HCV antibody, HBs antigen, ATLA virus antibody or HIV antibody positive person.
•12) Smoke more than 10 pieces per day.
•13) Have anti-coagulant or anti-platelet medications, or have a bleeding disorders.
•14) Other,the investigator believes makes him/her unsuitable for participation in the clinical study.

发起方

Tobita Morikuni