Platelet rich plasma transplantation for the periodontal tissue defects

Phase 1

Suspended

• Conditions: Chronic Periodontitis

• Registration Number: JPRN-jRCTc030190277
• Lead Sponsor: Tobita Morikuni

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2020-03-31
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Suspended
• Sex: All
• Target Recruitment: 2

Inclusion Criteria

1) Have a Periodontal pocket more than 5 mm at baseline examination.
2) Intrabony defect is 5 mm and more depth, and 2 mm and more width at interproximal site of the experimental tooth by X-ray examination.
3) Already have received initial preparation at the screening.
4) Mobility of experimental tooth is 0, 1, or 2, and exist keratinized gingiva.
5) Persons whose oral hygiene is established Good oral hygiene.
6) 20 years and older.
7) Signed informed consent

Exclusion Criteria

1) Can not be measured clinical attachment level of experimental tooth.
2) Have a history of Complicate malignant tumor.
3) Suspected of oral malignant tumor or precancerous lesion.
4) Need to undergo the treatment, such as surgical treatment, restorative treatment or root canal treatment, at the experimental tooth within 36 weeks after transplant.
5) Pregnancy, during breastfeeding, or possibility of pregnancy.
6) Persons who suffer from disorders of kidney, liver or blood
7) Have disease of kidney, liver and/or blood.
8) Have active infectious diseases.
9) Alcoholism or Drug dependence.
10) Mental or consciousness disorder.
11) HCV antibody, HBs antigen, ATLA virus antibody or HIV antibody positive person.
12) Smoke more than 10 pieces per day.
13) Have anti-coagulant or anti-platelet medications, or have a bleeding disorders.
14) Other,the investigator believes makes him/her unsuitable for participation in the clinical study.

Study & Design

• Study Type: Interventional
• Study Design: Not specified