ACTRN12613000895785Not yet recruiting未知
A pilot study to investigate the effects of one week of treatment with acetazolamide on the arterial levels of carbon dioxide in patients receiving non-invasive ventilation for the treatment of obesity hypoventilation syndrome
niversity of Otago, Wellington0 sites10 target enrollmentStarted: August 12, 2013Last updated:
Conditions
Trial Snapshot
- Phase
- 未知
- Status
- Not yet recruiting
- Sponsor
- Enrollment
- 10
Study Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Interventional
- Allocation
- Non-randomised trial
- Primary Purpose
- Treatment
- Masking
- Open (masking not used)
Eligibility Criteria
- Ages
- 18 Years to 99 Years (—)
- Sex
- All
Inclusion Criteria
- •Diagnosis of obesity hypoventilation syndrome
- •Currently receiving non-invasive ventilation in s-mode
- •No hospitalisation with decompensation of respiratory failure for at least 3 months
- •Willing and able to give informed consent
Exclusion Criteria
- •Unable to provide informed consent
- •Poor renal function (eGFR <30ml/min)
- •Poor compliance with non-invasive ventilation (average usage less than 4 hours per night)
- •Allergy or previous adverse reaction to sulphur drugs
- •Use of supplemental oxygen
- •Any other safety concern at investigators discression
Investigators
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