Training alcohol-related attentional biases in alcohol-dependence. What are the neurocognitive effects?
- Conditions
- Alcohol dependence
- Registration Number
- NL-OMON24784
- Lead Sponsor
- Department of Developmental psychology, University of AmsterdamDepartment of Psychiatry, Academic Medical Centre Amsterdam.
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 60
Inclusion Criteria
•Male and female patients, aged between 18-70 years
•Current DSM-V diagnosis of alcohol dependence
Exclusion Criteria
•Impairments in visual processing or in hand-eye coordination (this would make it difficult for patients to perform properly in the scanner)
•Being on any anti-craving medication (baclofen, acamprosate, naltrexone, disulfiram, or topiramate)
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method fMRI indices of attentional processing of alcohol-associated images will be taken both before and after the end of the training regimen. Changes in neural effects will be one outcome variable.<br><br /><br /><br>Changes in biases to alcohol-associated stimuli will also be investigated.<br><br /><br /><br>Propensity to relapse and number of drinks consumed and frequency of alcohol use in the month following the training
- Secondary Outcome Measures
Name Time Method Propensity to relapse and number of drinks consumed and frequency of alcohol use in the month following the training