TCTR20230615001已完成2 期
Effect of Roxadustat in management of anemia and iron regulation in cirrhosis of liver patients: a randomised control trial
适应症
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 入组人数
- 75
研究概览
简要总结
This is a randomized controlled trial conducted to evaluate the effect of roxadustat in increasing haemoglobin level and in iron regulation through decreasing hepcidin level with anemia in liver cirrhosis patients. In roxadustat treatment group, hemoglobin level and erythropoetin level increased and hepcidin level decreased after 6 weeks and these changes were statistically significant when compared with the changes of standard medical care group.
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 Years 至 65 Years（—）
- 性别
- All
入选标准
- •1. Patients with cirrhosis of liver (Child pugh A or B) 2. Anemia. 3. Age: More than 18 years
排除标准
- •1. Patients with Child Pugh C liver cirrhosis 2. Hepatocellular carcinoma 3. Pregnancy or lactation 4. Active variceal bleeding 5. Adult polycystic kidney disease 6. Hypo/Hyperthyroidism 7. Systemic Hypertension 8. Hyperkalemia 9. Patient with co-morbid condition (COPD, CKD, CCF, MI etc.)
研究者
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