International Multicentre Prevalence Study on Sepsis

Completed

• Conditions: Septic Shock; Severe Sepsis

• Registration Number: NCT01943747
• Lead Sponsor: European Society of Intensive Care Medicine

Brief Summary

To mark 10 years of the Surviving Sepsis Campaign (SSC), and timed to coincide with World Sepsis Day, on September 13, 2013, the SSC, ESICM and SCCM will be conducting an international point prevalence study of severe sepsis and septic shock. The goal of this project is to determine the world wide burden of severe sepsis and define current practices of sepsis care internationally. The study is a simple data collection exercise for patients presenting with either severe sepsis or septic shock on World Sepsis Day.

Detailed Description

De---identified patient---level data will be collected on patients presenting to a participating intensive care unit or emergency department with severe sepsis or septic shock over a 24 hour period from 00:00 to 24:00 November 07, 2013. De---identified data that is already collected as part of routine clinical care will be collected for this study. Data to be collected includes hospital and ICU characteristics, patient characteristics, severity of illness, and adherence to SSC bundle elements and mortality. It will take between 30---60 minutes to collect and enter data for each patient admitted with severe sepsis or septic shock over the 24 hours study period.

Study Timeline

• Study First Submitted: 2013-09-12
• Study First Submitted QC: 2013-09-16
• Study First Posted: 2013-09-17
• Study Start: 2013-11
• Primary Completion: 2013-11
• Study Completion: 2014-01
• Status Verified: 2014-08
• Last Update Submitted: 2014-08-19
• Last Update Posted: 2014-08-20

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 1000

Inclusion Criteria

To be eligible patients must have all of the following:

• Must be admitted or transferred to either the ED or an Intensive Care Unit.
• Have a high clinical suspicion of an infection
• Have sepsis as defined by an infection together with two or more SIRS criteria
• Evidence of acute organ dysfunction and/or Shock.

Exclusion Criteria

• Patients less than 18 years of age
• Patients in whom the sepsis has been present from before the beginning of the study period
• Any patients previously included in the study during the same study period

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
28-Day Mortality	one week

Secondary Outcome Measures

Name	Time	Method
Organ Failure	one week

Trial Locations

Locations (1)

All centres willing to contribute are welcome.; 🇧🇪 Brussels, Belgium