NCT04754243招募中4 期
A Higher Ovulation and Pregnancy Rates in Patients With Unexplained Infertility After Application of ANTIUI Protocol: A Randomized Multicenter Controlled Study
适应症
干预措施
相关药物
试验速览
- 阶段
- 4 期
- 状态
- 招募中
- 入组人数
- 200
- 试验地点
- 1
- 主要终点
- Ovulation
研究概览
简要总结
The new protocol ANTIUI provides good results regarding ovulation and pregnancy rates in patients with unexplained infertility
详细描述
Patients with unexplained infertility has normal investigations regarding hormonal, structural data. Semen is normal but no pregnancy occurs.
Before trying ICSI, we could help these patients with ANTIUI
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 35 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Unexplained infertility
- •Duration less than 5 years
- •Good ovarian reserve AMH> 1.1
- •Normal patent tubes
- •No previous trials of IUI with the same protocol
排除标准
- •Age > 35 years
- •Duration of infertility> 5 years
- •Abnormal semen
- •Hypoplastic tubes
- •prior failed ICSI
研究组 & 干预措施
Study group
Experimental
Will receive ANTIUI protocol
干预措施: Gonadotropin (Drug)
Control group
Active Comparator
Will receive standard protocol in IUI and unexplained infertility
干预措施: Standard protocol in IUI (Drug)
结局指标
主要结局
Ovulation
时间窗: 6 months
Disappearance of mature follicle
Pregnancy
时间窗: 6 months
Number of pregnant cases
次要结局
未报告次要终点
研究者
Ayman S Dawood, MD
Assistant professor
Tanta University
研究点 (1)
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