New Protocol in Unexplained Infertility

Phase 4

Recruiting

• Conditions: Unexplained Infertility
• Interventions: Drug: Gonadotropin; Drug: Standard protocol in IUI

• Registration Number: NCT04754243
• Lead Sponsor: Tanta University

Brief Summary

The new protocol ANTIUI provides good results regarding ovulation and pregnancy rates in patients with unexplained infertility

Detailed Description

Patients with unexplained infertility has normal investigations regarding hormonal, structural data. Semen is normal but no pregnancy occurs.

Before trying ICSI, we could help these patients with ANTIUI

Basic Information
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Recruitment & Eligibility
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Study & Design
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Trial Locations

Study Timeline

• Study First Submitted: 2021-02-10
• Study First Submitted QC: 2021-02-12
• Study First Posted: 2021-02-15
• Study Start: 2021-03-01
• Status Verified: 2023-07
• Last Update Submitted: 2023-07-15
• Last Update Posted: 2023-07-18
• Primary Completion: 2024-12-31
• Study Completion: 2024-12-31

Recruitment & Eligibility

• Status: RECRUITING
• Sex: Female
• Target Recruitment: 200

Inclusion Criteria

• Unexplained infertility
• Duration less than 5 years
• Good ovarian reserve AMH> 1.1
• Normal patent tubes
• No previous trials of IUI with the same protocol

Read More

Exclusion Criteria

• Age > 35 years
• Duration of infertility> 5 years
• Abnormal semen
• Hypoplastic tubes
• prior failed ICSI

Read More

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Study group	Gonadotropin	Will receive ANTIUI protocol
Control group	Standard protocol in IUI	Will receive standard protocol in IUI and unexplained infertility

Primary Outcome Measures

Name	Time	Method
Ovulation	6 months	Disappearance of mature follicle
Pregnancy	6 months	Number of pregnant cases

Trial Locations

Locations (1)

Ayman Shehata Dawood; 🇪🇬 Tanta, Gharbia, Egypt