跳至主要内容
临床试验/CTRI/2022/02/040099
CTRI/2022/02/040099招募中不适用

To evaluate the effects of Yoga on Cognitive function, activities of daily living, self-reported Depression, and Heart Rate Variability in subjects with Vascular Dementia

Central Council for Research in Yoga and Naturopathy Ministry of AYUSH1 个研究点 分布在 1 个国家目标入组 104 人开始时间: 2022年2月14日最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
发起方
入组人数
104
试验地点
1
主要终点
Cognitive Functions

研究概览

简要总结

Yoga-based interventions appear to significantly improve several cognitive domains in elderly such as immediate and delayed recall, verbal and visual memory, attention, working memory, verbal fluency, executive function, and processing speed. Yoga has emerged as an effective and feasible add on therapy in schizophrenia, with special benefits in improving social cognition and negative symptoms. Yoga was found to benefit individuals with depressive symptoms, including quality of life and cognition. Some of the consistent effects of yoga practice include stress reduction, emotion regulation, improved mood and well being. Though, the studies have shown the beneficial effect of Yoga in improving the cognitive functions, no study till date has been studied to understand the role of Yoga in Vascular Dementia. The study will evaluate the effect of yoga on cognitive functions, self reported Dementia, the activity of daily living, and heart rate variability in Vascular dementia patients who are undergoing conventional therapy. This study is a randomized controlled trial, where we will compare two groups, case group - yoga intervention integrated with conventional treatment and control group. There will be 52 participants in each group diagnosed with vascular dementia by the specialist. Assessments of variables will be done at baseline and completion of 8 weeks. The intervention will be given for 8 weeks to all the participants in the case group.

研究设计

研究类型
Interventional
分配方式
Computer generated randomization
盲法
Open Label

入排标准

年龄范围
55.00 Year(s) 至 75.00 Year(s)(—)
性别
All

入选标准

  • •1.Diagnosed case of Vascular Dementia as per DSM V.
  • •2.Age above 55 – 75 years 3.Zubrods performance status 1-2.

排除标准

  • •1.Dementia due to any other etiology 2.History of recent /past Head Injury resulting in neurologic deficits 3.History of Neurosurgery-Craniotomy 4.History of Substance Dependence other than Nicotine 5.Those with prior h/o depression, a major psychiatric illness associated with cognitive illness 6.Those with brain metastases 7.Concurrent medical condition likely to influence survival 8.Uncontrolled diabetes, hypertension, and autoimmune disease 9.Neurological disorders such as any significant head injury, epilepsy, Parkinson’s disease, neurodegenerative disorders, etc.
  • •10.Regular participation in an active behavioral intervention/yoga in the last six months 11.H/o recent brain infections or fever in the past two months (meningitis/encephalitis) 12.Those with anemia (Hemoglobin < 10gm %) 13.LVEF<40% 14.H/o recent atrial fibrillation.

结局指标

主要结局

Cognitive Functions

时间窗: Before and after 2 months

次要结局

  • Heart Rate Variability(Before and after 2 months)
  • Activities of Daily living(Before and after 2 months)
  • Self-reported Depression(Before and after 2 months)

研究者

发起方
Central Council for Research in Yoga and Naturopathy Ministry of AYUSH
申办方类型
Government funding agency

研究点 (1)

Loading locations...

相似试验

Yoga Therapy for dementia in elderly with vascular... | 临床试验