To take patient off breathing machine support (Ventilator)by examining breathing muscle (diaphragm) with ultrasound.
Not Applicable
- Conditions
- Health Condition 1: J986- Disorders of diaphragm
- Registration Number
- CTRI/2023/09/057314
- Lead Sponsor
- A
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
(1) Age = 18 years
(2) On mechanical ventilation for more than 12 h
(3) Meeting all of the following criteria for the SBT:
a.FiO2 <40%
b.Positive end-expiratory pressure =5 cmH2O
c.Respiratory rate=30 breaths/min
d.Haemodynamic stability in the absence/ minimal vasopressors
Exclusion Criteria
1.Age <18 years
2.Neuromuscular diseases
3.Flail chest or multiple rib fracture
4.Morbid obesity (BMI > 40 kg/m2)
5.Inability to obtain a clear TDI signal of the right hemidiaphragm
6.Pregnant patient.
7.Tracheostomised patient
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Correlation of diaphragmatic kinetics (Peak contraction velocity, peak relaxation velocity, velocity time integral, maximal relaxation rate) with weaningTimepoint: Just before the Spontaneous Breathing Trial.
- Secondary Outcome Measures
Name Time Method Incidence of reintubation within 48 hours of extubation.Timepoint: Within 48 hours of extubation.