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Clinical Trials/NCT06483971
NCT06483971Active, not recruitingNot Applicable

Comparison of Oral Isotretinoin Versus Ancomparison of Oral Isotretinoin Versus Antibiotics on Corneal Thickness in Patients With Acne Vulgaris

Superior University1 site in 1 country36 target enrollmentStarted: November 1, 2023Last updated:
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Conditions

Trial Snapshot

Phase
Not Applicable
Status
Active, not recruiting
Enrollment
36
Locations
1
Primary Endpoint
Optical Coherence Tomography (OCT)
Study OverviewStudy DesignEligibility CriteriaOutcomesInvestigatorsSitesRecords & IdentifiersSimilar Trials

Study Overview

Brief Summary

Comparison of Oral Isotretinoin versus comparison of Oral Isotretinoin versus Antibiotics on Corneal Thickness in Patients with Acne Vulgaris

Detailed Description

Acne is the most common skin disease requiring attention of health practitioners. It is a self-limiting disease of the pilosebaceous unit, which can lead to devastating and frustrating scars and pigmentary alterations.

Study Design

Study Type
Interventional
Allocation
Randomized
Intervention Model
Parallel
Primary Purpose
Health Services Research
Masking
None

Eligibility Criteria

Ages
20 Years to 43 Years (Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • •Patients of either gender shall be enrolled for this study.
  • •Acne vulgaris patients taking oral isotretinoin and oral antibiotics shall be included.

Exclusion Criteria

  • •Patients with any ocular pathology shall be excluded.
  • •Patients with any systemic pathology other than acne vulgaris shall be excluded.
  • •Patients with history of contact lens wear, previous refractive surgery or injury shall be excluded.

Outcomes

Primary Outcomes

Optical Coherence Tomography (OCT)

Time Frame: 12 Months

Standardized OCT imaging protocols to ensure consistency and accuracy across all measurements.

Snellen Chart

Time Frame: 12 months

Visual acuity measured at 3-month and 6-month intervals. Units: Snellen fraction (e.g., 20/20, 20/40)

Secondary Outcomes

No secondary outcomes reported

Investigators

Sponsor Class
Other
Responsible Party
Principal Investigator
Principal Investigator

Muhammad Naveed Babur

Principal Investigator

Superior University

Study Sites (1)

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