Comparison of Oral Isotretinoin Versus Ancomparison of Oral Isotretinoin Versus Antibiotics on Corneal Thickness in Patients With Acne Vulgaris
试验速览
- 阶段
- 不适用
- 状态
- 进行中（未招募）
- 入组人数
- 36
- 试验地点
- 1
- 主要终点
- Optical Coherence Tomography (OCT)
研究概览
简要总结
Comparison of Oral Isotretinoin versus comparison of Oral Isotretinoin versus Antibiotics on Corneal Thickness in Patients with Acne Vulgaris
详细描述
Acne is the most common skin disease requiring attention of health practitioners. It is a self-limiting disease of the pilosebaceous unit, which can lead to devastating and frustrating scars and pigmentary alterations.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Health Services Research
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 43 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients of either gender shall be enrolled for this study.
- •Acne vulgaris patients taking oral isotretinoin and oral antibiotics shall be included.
排除标准
- •Patients with any ocular pathology shall be excluded.
- •Patients with any systemic pathology other than acne vulgaris shall be excluded.
- •Patients with history of contact lens wear, previous refractive surgery or injury shall be excluded.
研究组 & 干预措施
Antibiotics
干预措施: Antibiotics (Combination Product)
Oral Isotretinoin
干预措施: Oral Isotretinoin (Diagnostic Test)
结局指标
主要结局
Optical Coherence Tomography (OCT)
时间窗: 12 Months
Standardized OCT imaging protocols to ensure consistency and accuracy across all measurements.
Snellen Chart
时间窗: 12 months
Visual acuity measured at 3-month and 6-month intervals. Units: Snellen fraction (e.g., 20/20, 20/40)
次要结局
未报告次要终点
研究者
Muhammad Naveed Babur
Principal Investigator
Superior University