Efficacy of K-Y Jelly in Prevention of Postoperative Sore Throat After Nasal Surgery

Phase 4

• Conditions: Postoperative Sore Throat
• Interventions: Drug: K-Y Jelly, Topical Gel soaked packs; Other: Water soaked packs

• Registration Number: NCT05436743
• Lead Sponsor: Alaa Gamal

Brief Summary

Postoperative sore throat (POST) is a fairly common side effect of general anesthesia which is caused by the mucosal injury and nerve compression associated with tracheal intubation or laryngeal mask airway device insertion. In this randomized study, the authors evaluate the effect of K-Y jelly-soaked nasopharyngeal packs on POST and postoperative nausea and vomiting in patients subjected to nasal surgery.

Detailed Description

Postoperative sore throat (POST) is a fairly common side effect of general anesthesia which is caused by the mucosal injury and nerve compression associated with tracheal intubation or laryngeal mask airway device insertion. In this randomized study, the authors evaluate the effect of K-Y jelly-soaked nasopharyngeal packs on POST and postoperative nausea and vomiting in patients subjected to nasal surgery.

The present double-blinded randomized controlled study was conducted at Al-Azhar University Hospitals, Cairo, Egypt. The study protocol was approved by the local ethical committee of Al-Azhar Faculty of Medicine and all patients provided informed consent before enrollment in the study.

Study Timeline

• Study First Submitted: 2021-12-16
• Status Verified: 2022-06
• Study First Submitted QC: 2022-06-28
• Last Update Submitted: 2022-06-28
• Study First Posted: 2022-06-29
• Last Update Posted: 2022-06-29
• Study Start: 2022-07-01
• Primary Completion: 2022-08-01
• Study Completion: 2022-08

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 140

Inclusion Criteria

• Patients submitted to nasal surgery under general anesthesia.

Exclusion Criteria

• Acute of chronic nasopharyngeal conditions,
• Gastroesophageal reflux, regurgitation,
• History of postoperative sore throat,
• nasal surgery for malignant disease,
• concurrent or recent use of systemic or topical agents used for sore throat or
• Mallampati grade more than 2.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
K-Y jelly soaked packs	K-Y Jelly, Topical Gel soaked packs	K-Y jelly soaked packs inserted for pretension of postoperative sore throat
Water soaked packs	Water soaked packs	Water soaked packs inserted for pretension of postoperative sore throat

Primary Outcome Measures

Name	Time	Method
Postoperative sore throat	up to 6 hours postoperatively	Postoperative sore throat

Trial Locations

Locations (1)

Al-Azhar University Hospitals; 🇪🇬 Cairo, Egypt