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Clinical Trials/NCT03850223
NCT03850223
Unknown
Not Applicable

Clinical Audit On Management Of Congenital Heart Disease In Assiut Children University Hospital

Assiut University0 sites100 target enrollmentMarch 1, 2020

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Congenital Heart Disease
Sponsor
Assiut University
Enrollment
100
Primary Endpoint
Clinical audit study to assess management of congenital heart disease in AUCH
Last Updated
6 years ago

Overview

Brief Summary

Congenital Heart Disease (CHD) is the most common birth defect in the United States, affecting approximately 0.8% of live births. Improved treatment strategies and interventions have increased survival such that 85% to 90% of affected children are expected to live well into adulthood, thereby causing a demographic shift in which adults now outnumber children with CHD, and more people with complex CHD are living longer.

Detailed Description

CHD may be defined as an anatomic malformation of the heart or great vessels which occurs during intrauterine development, irrespective of the age at presentation. The cause of most congenital heart defects is still unknown. Many cases of congenital heart disease are multifactorial and result from a combination of genetic predisposition and an environmental stimulus. A small percentage of congenital heart lesions are related to known chromosomal abnormalities, in particular, trisomy 21, 13, and 18 and Turner syndrome. Of all cases of congenital heart disease, 2-4% are associated with known environmental or adverse maternal conditions and teratogenic influences, including maternal diabetes mellitus, phenylketonuria, systemic lupus erythematosus or congenital rubella syndrome; and maternal ingestion of drugs (lithium, ethanol, warfarin, antimetabolites, vitamin A derivatives, anticonvulsant agents).

Registry
clinicaltrials.gov
Start Date
March 1, 2020
End Date
December 1, 2021
Last Updated
6 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Fadwa Magdy Mohamed Abdou

Principle investigator

Assiut University

Eligibility Criteria

Inclusion Criteria

  • children with CHD more than one month

Exclusion Criteria

  • children with CHD less than one month

Outcomes

Primary Outcomes

Clinical audit study to assess management of congenital heart disease in AUCH

Time Frame: One year

To assess how much the adopted protocol of management of congenital heart disease is implemented in Assiut university children hospital

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