Clinical Practice Guideline for Neonatal Extravasation Injury

Not Applicable

Completed

• Conditions: Extravasation Injury
• Interventions: Other: Clinical practice guideline for prevention and management of extravasation injury

• Registration Number: NCT04321447
• Lead Sponsor: United Christian Hospital

Brief Summary

This study is aimed to evaluate the effectiveness of an evidence-based clinical practice guideline in the prevention and management of neonatal extravasation injury, and to examine the change in nurses' knowledge of and adherence to the guideline.

Detailed Description

A study with controlled before-and-after design was conducted. The clinical practice guideline was developed and a multifaceted educational program was delivered for nurses. Neonatal outcomes were collected at baseline and after completion of the intervention. The changes in nurses' level of knowledge and adherence to the guideline were also measured.

Study Timeline

• Study Start: 2015-11-14
• Primary Completion: 2016-11-23
• Study Completion: 2017-08-29
• Status Verified: 2020-03
• Study First Submitted: 2020-03-20
• Study First Submitted QC: 2020-03-23
• Last Update Submitted: 2020-03-23
• Study First Posted: 2020-03-25
• Last Update Posted: 2020-03-25

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 213

Inclusion Criteria

• Neonates who were admitted for intravenous medication or infusion therapy, and
• Neonates whose parents were equal to or over 18 years old and able to communicate in Chinese or English.

Exclusion Criteria

• Neonates who were born with congenital dermatological problems such as ichthyosis and epidermolysis bullosa.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SEQUENTIAL

Arm && Interventions

Group	Intervention	Description
Clinical practice guideline (CPG) group	Clinical practice guideline for prevention and management of extravasation injury	Implementation of an evidence-based clinical practice guideline and delivery of an educational programme

Primary Outcome Measures

Name	Time	Method
Change in rate of peripheral intravenous extravasation	Change from Baseline rate at one month	The number of the incidents divided by the total number of catheter days and multiplied by 1,000
Change in rate of extravasation from a central line	Change from Baseline rate at one month	The number of the incidents divided by the total number of catheter days and multiplied by 1,000

Secondary Outcome Measures

Name	Time	Method
Change in nurses' level of knowledge	Change from Baseline Knowledge level at six months	The Neonatal Extravasation Knowledge Test
Change in nurses' adherence to clinical practice guidelines	Change from Baseline Adherence level at six months	A 27-item audit tool