Comparison of the Effects of Core Stabilization and Inspiratory Muscle Training on Diaphragm Activation, Inspiratory Muscle Strength, Functional Capacity, Respiratory Functions, Physical Activity and Quality of Life in Patients With COPD
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Enrollment
- 36
- Locations
- 1
- Primary Endpoint
- Symptoms
Study Overview
Brief Summary
In Chronic Obstructive Pulmonary Disease (COPD), a mismatch develops between the respiratory system's demand and the functional capacity of respiratory muscles due to the combination of local and systemic factors increasing the respiratory workload. This results in impaired coordination of muscle groups, leading to muscle dysfunction. Respiratory muscle dysfunction is a significant determinant of life expectancy in COPD. Additionally, respiratory muscles unable to cope with increased workloads lead to impaired respiratory functions and reduced exercise capacity.
It is widely accepted that appropriate training of respiratory muscles can increase their strength, endurance, and their close relationship with lung volume capacities. Besides their role in respiration, respiratory muscles also contribute to postural function and core stabilization. Studies on respiratory muscle training in COPD have primarily focused on inspiratory muscle strength training, neglecting the core stabilization function of respiratory muscles. However, optimal gains in a muscle can only be achieved with training tailored to its functional characteristics. Therefore, a comprehensive training program should be developed considering the multifunctional nature of respiratory muscles. Studies published in healthy individuals and different patient populations demonstrate that core training can improve lung functions. The aim of this study is to compare the effects of inspiratory muscle training and core stabilization training on diaphragm activation, inspiratory muscle strength, functional capacity, respiratory functions, physical activity, and quality of life in individuals with COPD.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- None
Eligibility Criteria
- Ages
- 18 Years to 85 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Being over 18 years old
- •Having a diagnosis of COPD according to the GOLD criteria and being at stage 3 or lower
- •Not being in an acute exacerbation period and having at least one month since the last exacerbation
- •Being able to walk independently
- •Having sufficient mental capacity to understand the tasks in the study (Mini-Mental Test >24)
- •Being willing to participate in the study
Exclusion Criteria
- •Being a stage 4 COPD patient according to the GOLD criteria
- •Having a diagnosis of lung cancer, pulmonary hypertension, and heart failure
- •Being in a COPD exacerbation period
- •Scoring below 24 on the Mini-Mental Test
- •Having any other disease that affects respiratory functions
- •Having undergone pulmonary surgery
Outcomes
Primary Outcomes
Symptoms
Time Frame: 8 weeks
MMRC Dyspnea Scale (Scores range from 0 to 4)
Inspiratory Muscle Strength
Time Frame: 8 weeks
Maximal Inspiratory Pressure (MIP) (cmH2O),
Respiratory function tests PEF
Time Frame: 8 weeks
Spirometry, PEF (lt/sn)
Inspiratory Muscle Activation
Time Frame: 8 weeks
surface EMG (TLC from FRC (TLC maneuver)(cmH2O)
Respiratory function tests FEV1
Time Frame: 8 weeks
Spirometry, FEV1 (lt)
Respiratory function tests FVC
Time Frame: 8 weeks
Spirometry, FVC (lt)
Respiratory function tests FEV1/FVC
Time Frame: 8 weeks
Spirometry, FEV1/FVC %
Respiratory function MVV
Time Frame: 8 weeks
Spirometry, MVV(L/min)
Functional capacity
Time Frame: 8 weeks
Six Minute Walking Test (6MVT) (m)
Secondary Outcomes
- Physical activity,(8 week)
- Quality of life Tests(8 week)
- Core Strength extension(8 week)
- Core Strength(8 week)
- Core Strength flexion(8 week)
- Core Strength side bridge(8 week)
Investigators
Mustafa Ertuğrul Yaşa
assistant professor
Gulhane School of Medicine
