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临床试验/NCT00221052
NCT00221052已完成不适用

Relation Between Reduction of the Inflammatory Status and Glucose Metabolism in Healthy Overweight Men

TNO2 个研究点 分布在 1 个国家目标入组 20 人开始时间: 2005年6月最近更新:
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相关药物

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
20
试验地点
2

研究概览

简要总结

Overweight increases the risk to develop chronic diseases including type-2 diabetes and cardiovascular disease. The low-grade inflammatory status often seen in overweight subjects is thought to play an important role in disease development.

The purpose of this study is to determine the role of inflammation on glucose metabolism and insulin resistance. In this study the effect of the anti-inflammatory treatment diclofenac on markers of inflammation and on parameters of glucose metabolism will be studied.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
盲法
Double

入排标准

年龄范围
18 Years 至 60 Years(Adult)
性别
Male
接受健康志愿者

入选标准

  • Body Mass Index (BMI): 25.1 - 32.0 kg/m2
  • Normal Dutch eating habits

排除标准

  • diabetes, cardiovascular disease or hypertension
  • Not suitable to receive diclofenac treatment
  • Extreme physical activity (more than 6 hours/week)
  • Reported slimming or medically prescribed diet

研究者

发起方
TNO
申办方类型
Other

研究点 (2)

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