Study to see the requirement of of Pain injection dose in Breast Surgery
- Conditions
- Medical and Surgical,
- Registration Number
- CTRI/2022/07/043777
- Lead Sponsor
- Nizams Institute of Medical sciences
- Brief Summary
After obtaining institutional ethical commitee approval and CTRI acknowledgement number, and written informed consent from patients, A prospective randomised controlled study will be conducted in 30 ASA I-II female patients aged 18 to 65 years undergoing mastectomy under general anaesthesia and amount of fentanyl consumption will be compared between haemodynamic and SPI guidance. Patients refusing, allergic to fentanyl, hypertension, on beta blockers, cvs, CNS, renal and respiratory diseases will be excluded. Patients will be advised fasting 8 hours before surgery and administered rantac and alprozolam tablets. Later the patients will be shifted to OT, connected to monitors: NIBP, ECG, SPI, spo2, ETCO2 and IV fluid administered, Baseline VITALS: HR, RR, SPO2, SBP.DBP, MAP noted. Patients will be premedicated with iv fentanyl, glycopyrolate, induced and later intubated and connected to ventilator. Vitals will be noted every 5 minutes till end of surgery and fentanyl requirement will be recorded. Later at the end of surgery patient will be extubated. Degree of postop pain, dose of first rescue analgesic requirement , extubation and any adverse events will be noted.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Not Yet Recruiting
- Sex
- Female
- Target Recruitment
- 30
1.18 – 65 years 2.ASA grade I and II 3.Females 4.Scheduled for elective mastectomy.
1.Patient Refusal 2.Known allergy to Fentanyl drug 3.Hypertension & those on beta blockers 4.Cardiovascular disease, Cardiac arrhythmias, drugs influencing HR, Pacemakers 5.Previous Sympathectomy, Vagotomy 6.Respiratory disorder like asthma 7.Neurologic disorders like Seizures 8.Renal disease 9.Patients on chronic medication like analgesics or psychiatric medication.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method intraoperative dose of fentanyl requirement baseline till end of surgery
- Secondary Outcome Measures
Name Time Method 1.postop rescue analgesic requirement 2. extubation time
Trial Locations
- Locations (1)
Nizams institute of medical sciences
🇮🇳Hyderabad, TELANGANA, India
Nizams institute of medical sciences🇮🇳Hyderabad, TELANGANA, IndiaSingam GeethaPrincipal investigator9441043075singamgeetha11@gmail.com