COMPARISON OF INTRAVENOUS LABETALOL,INTRAVENOUS HYDRALAZINE AND ORAL NIFEDIPINEFOR ACUTE BLOOD PRESSURE CONTROL INHYPERTENSIVE EMERGENCIES IN PREGNANCY:A RANDOMIZED DOUBLE BLIND TRIA

niversity College of Medical Sciences and associated Guru Teg Bahadur Hospital0 个研究点目标入组 105 人开始时间: 待定最近更新: 2021年11月24日

试验速览

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•1. Pregnant women beyond 20 weeks gestation or during intrapartum period detected to have a systolic BP more than equal to 160 mm Hg or diastolic BPmore than equal to 110 mmHg will be recruited. These patients could be
•a. Cases of gestational hypertension with no previous antihypertensive therapy.
•b. Cases of gestational hypertension with previous antihypertensive therapy other than Labetalol, Hydralazine or Nifedipine
•c. Cases of gestational hypertension with superimposed pre-eclampsia
•d. Cases of severe preeclampsia, HELLP syndrome with systolic BP ï?³160 mm Hg and/or diastolic BP >=110 mmHg.
•2. Women willing to participate in the study with informed written consent.

•1. Eclampsia
•2. Cases presenting with pulmonary edema
•3. Cases of severe hypertension in pregnancy with impaired state of consciousness or altered sensorium
•4. Women with history of heart disease, asthma, renal disease
•5. Intake of any of the drugs being studied, in preceding 72 hours
•6. Women presenting with history of allergy to any of the drugs being studied or developing adverse effects requiring discontinuation of therapy

发起方

niversity College of Medical Sciences and associated Guru Teg Bahadur Hospital