COMPARISON OF EFFICACY OF 3 DRUGS FOR MANAGING ACUTE HYPERTENSION EMERGENCY IN PREGNANCY

Phase 4

• Conditions: Health Condition 1: null- Pregnant women beyond 20 weeks gestation or during intrapartum period detected to have a systolic BP more than equal to 160 mm Hg or diastolic BP more than equal to 110 mm Hg will be recruited.

• Registration Number: CTRI/2015/04/005683
• Lead Sponsor: niversity College of Medical Sciences and associated Guru Teg Bahadur Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 24 November 2021

Recruitment & Eligibility

• Status: Open to Recruitment
• Sex: Not specified
• Target Recruitment: 105

Inclusion Criteria

1. Pregnant women beyond 20 weeks gestation or during intrapartum period detected to have a systolic BP more than equal to 160 mm Hg or diastolic BPmore than equal to 110 mmHg will be recruited. These patients could be

a. Cases of gestational hypertension with no previous antihypertensive therapy.

b. Cases of gestational hypertension with previous antihypertensive therapy other than Labetalol, Hydralazine or Nifedipine

c. Cases of gestational hypertension with superimposed pre-eclampsia

d. Cases of severe preeclampsia, HELLP syndrome with systolic BP ï?³160 mm Hg and/or diastolic BP >=110 mmHg.

2. Women willing to participate in the study with informed written consent.

Exclusion Criteria

1. Eclampsia

2. Cases presenting with pulmonary edema

3. Cases of severe hypertension in pregnancy with impaired state of consciousness or altered sensorium

4. Women with history of heart disease, asthma, renal disease

5. Intake of any of the drugs being studied, in preceding 72 hours

6. Women presenting with history of allergy to any of the drugs being studied or developing adverse effects requiring discontinuation of therapy

Study & Design

• Study Type: Interventional
• Study Design: Not specified