ACTRN12624001183572尚未招募2 期
Effect of SGLT2 inhibitors on cerebral injury and outcomes in comatose Out-Of-Hospital Cardiac Arrest survivors - a pilot study
适应症
试验速览
- 阶段
- 2 期
- 状态
- 尚未招募
- 入组人数
- 120
- 主要终点
- Composite of adverse events, including mortality, ketoacidosis, renal failure requiring renal replacement therapy, genitourinary infection and hypoglycaemia.[Peripheral blood and urine samples. Assessed daily for 30 days following comatose cardiac arrest.]
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Prevention
- 盲法
- Blinded (masking used)
入排标准
- 年龄范围
- 18 Years 至 No limit（—）
- 性别
- All
入选标准
- •Consecutive adults aged 18 years or older presenting with comatose out-of-hospital cardiac arrest suspected to be caused by acute coronary syndrome (ACS) as defined as either ST-elevation myocardial infarction (STEMI) or non-ST-elevation myocardial infarction (NSTEMI).•Total downtime prior to return of spontaneous circulation of less than 30 minutes.
排除标准
- •Patients with a history of type 1 diabetes•Patients already treated with an SGLT2 inhibitor•Patients with an eGFR <25 ml/min/1.73m2 or receiving dialysis
结局指标
主要结局
Composite of adverse events, including mortality, ketoacidosis, renal failure requiring renal replacement therapy, genitourinary infection and hypoglycaemia.[Peripheral blood and urine samples. Assessed daily for 30 days following comatose cardiac arrest.]
次要结局
未报告次要终点
研究者
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