to compare the effectiveness between nebulized budesonide and nebulized dexamethasone in reducing post operative cough in patients undergoing surgery under general anaesthesia
Not Applicable
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2022/09/045261
- Lead Sponsor
- Department of Anaesthesiology SMS Medical College and Hospitals
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Age between 18 to 60 years
2.American Society of Anesthesiologists (ASA) physical status I-II
3.Scheduled for surgeries in the supine position under general anesthesia with endotracheal intubation.
4.Duration of surgery less than 3 hours.
Exclusion Criteria
1.Patients already having upper respiratory tract infection or sore throat
2.Patients already on steroids: inhaled or oral
3.Patients already on analgesics
4.Patients with anticipated difficult airway with more than 2 attempts at intubation
5.Patient with history of bronchial asthma
6.Patients with nasogastric tube
7.Patients undergoing surgery of: oral cavity, head and neck, thyroid, tonsillectomies and cervical spine
8.History of allergy to the test drugs
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Post-operative coughTimepoint: 5 mins, 30 mins, 1 hr, 6 hrs after extubation
- Secondary Outcome Measures
Name Time Method Hemodynamic parameters (HR, SBP, DBP, MAP)Timepoint: baseline,before and after intubation,2mins,4mins,6 mins,8mins,10mins,15mins,20 mins,25 mins,30 mins after extubtion;post operative hoarsness of voiceTimepoint: 5 mins, 30 mins, 1 hr, 6 hrs after extubation;post operative sore throatTimepoint: 5 mins, 30 mins, 1 hr, 6 hrs after extubation