Conservative management of ductus in preterm neonates
Phase 3
- Conditions
- Health Condition 1: null- Preterm neonates below 32 weeks gestation
- Registration Number
- CTRI/2018/03/012784
- Lead Sponsor
- Dr Manoj Modi
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
All of following
1.Neonates with gestational age below 32 weeks, 2.Receiving mechanical ventilation
3.Having patent ductus arteriosus with duct diameter >1.5 and left atrium to aottic root ratio >1.5
Exclusion Criteria
1.Neonates with congenital heart disease
2.Neonates with persistent pulmonary hypertension of newborn
3.Failure to obtain parental consent
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Death or moderate to severe broncho-pulmonary dysplasiaTimepoint: at discharge from NIC
- Secondary Outcome Measures
Name Time Method Duration of mechanical ventilationTimepoint: discharge from NICU;intraventricular hemorrhageTimepoint: discharge from NICU;moderate to severe hearing lossTimepoint: discharge from NICU;mortality during NICU stayTimepoint: discharge from NICU;necrotizing enterocolitisTimepoint: discharge from NICU;Periventricular leucomalaciaTimepoint: discharge from NICU;pharmacological treatment for PDATimepoint: discharge from NICU;Retinopathy of prematurityTimepoint: discharge from NICU;Surgical ligations for PDATimepoint: discharge from NICU;use of postnatal steroids for facilitation of extubationTimepoint: discharge from NIC