Skip to main content
Clinical Trials/NCT04393402
NCT04393402
Completed
Not Applicable

Lung Ultrasound Score in Covid 19 Infectious Disease in Critical Care

Centre Hospitalier Universitaire de Nice1 site in 1 country14 target enrollmentMarch 20, 2020
ConditionsCOVID

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
COVID
Sponsor
Centre Hospitalier Universitaire de Nice
Enrollment
14
Locations
1
Primary Endpoint
LUS applicability with COVID 19
Status
Completed
Last Updated
last year

Overview

Brief Summary

It might be necessary with Sars-Cov2 pneumopathy patient to repeat thoracic images, the tomodensitometry ones in particular. This task is difficult and nearly impossible for several reasons: respiratory and hemodynamic unstable patient, prone position and due to the high contagious nature of the disease.

The lung ultrasound is an easy tool, fast (between 5 and 10 minutes) and as a limited training.

In the context of the Sars-Cov2 epidemic, Buonsenso and al case report depict the first lung ultrasound for a Covid 19 patient.

Peng and al in Intensive Care Medicine accentuate the usefulness of this particular technic.

In the American Journal of Respiratory and Critical Care Medicine, a study has been published as a point-of-care, in which the doctors reported using the lung ultrasound with intensive and critical care patient.

In Critical Care 2016, it has been showed that ultrasound allowed with neat precisions, to predict severe ARDS patient response to the prone position, all-cause.

Another researchers team found a good correlation between lung ultrasound, the SOFA, APACHE II, CPIS score, and patient mortality.

And a new applicability in the pulmonary recruitment by PEEP titration has been presented.

The aim of this study is to evaluate the lung ultrasound in Covid19 ARDS.

Registry
clinicaltrials.gov
Start Date
March 20, 2020
End Date
December 31, 2022
Last Updated
last year
Study Type
Observational
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Diagnosed Sars-Cov2 patient, with PCR method qualitative or quantitative as usual.
  • Intensive or critical care admission
  • ARDS with PaO2/FiO2 \<300 at the admission
  • Ventilatory support or oxygen-therapy

Exclusion Criteria

  • Age \< 18 years-old
  • Pregnancy
  • Patient with tutor- or curatorship or in prison

Outcomes

Primary Outcomes

LUS applicability with COVID 19

Time Frame: 10 months

In dorsal position, or in prone position, the two hemithorax will be subdivided in 6 parts, and a score will be attributed with the following criteria : A-Lines (0 point), \> 3 B-lines (1 point), B-Lines coalscent (2 points), and pulmonary consolidation (3 points). For the echography we can use a convexe sonde, or a "cardiac" sonde.

Secondary Outcomes

  • Radiographic correlation (chest Xray and tomodensitometry)(10 months)
  • LUS Mortality prediction(10 months)
  • Prediction of Prone position response(10 months)

Study Sites (1)

Loading locations...

Similar Trials