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Clinical Trials/EUCTR2006-006514-15-GB
EUCTR2006-006514-15-GB
Active, not recruiting
Not Applicable

Double blind crossover randomised controlled trial comparing letrozole versus clomifene citrate for ovulation induction in women with polycystic ovarian syndrome

The University of Nottingham0 sitesJanuary 16, 2007
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ConditionsInfertility due to polycycstic ovarian syndromeMedDRA version: 8.1Level: LLTClassification code 10021935Term: Infertility, female, associated with anovulation
DrugsFemaraClomid

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Infertility due to polycycstic ovarian syndrome
Sponsor
The University of Nottingham
Status
Active, not recruiting
Last Updated
10 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
January 16, 2007
End Date
TBD
Last Updated
10 years ago
Study Type
Interventional clinical trial of medicinal product
Sex
Female

Investigators

Eligibility Criteria

Inclusion Criteria

  • •1\. Women aged 18 \- 39
  • •2\. BMI \< 35
  • •3\. Infertility due to anovulation
  • •4\. Diagnostic criteria: at least 2 of the following criteria of PCOS have to be fulfilled:
  • •a) clinical: oligo/amenorrhoea
  • •b) hyperandrogenenaemia: biochemical (testosterone \>2\.5 nmol/l or free androgen index (FAI) \>5\) or clinical (acne/hirsutism) evidence
  • •c) USS evidence of PCO (either \>12 follicles measuring 2\-9mm in diameter, or an ovarian volume of 10ml)
  • •5\. No recent (within 6 months) treatment for induction of ovulation
  • •6\. Normal semen analysis (WHO 1999\)
  • •7\. Proven patency of at least one Fallopian tube

Exclusion Criteria

  • •1\. Inability to give informed consent
  • •2\. Contraindication to letrozole or cloifene citrate
  • •3\. The absence of any inclusion criteria

Outcomes

Primary Outcomes

Not specified

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