Scivias study - New biomarkers for diseases in childhood
Recruiting
- Conditions
- Diseases in childhood with an emphasis on disorders of the immune system and metabolism
- Registration Number
- DRKS00023566
- Lead Sponsor
- Klinikum der Universität München
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 5000
Inclusion Criteria
1. Age between 3 and 18 years
2. Existing consent (informed consent and informed assent)
Exclusion Criteria
no cooperation by the child (no informed assent)
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Primary study objective:<br>Identification of new biomarkers for the overall assessment of the systemic health status of children
- Secondary Outcome Measures
Name Time Method Secondary study objectives:<br>1. Establishment of a normal range for fundus photography, OCT and OCT angiography with regard to retinal changes in various age groups<br>2. Evaluation of the value of optical fundus evaluation in (early) diagnosis of a rare disease<br>3. Establishing a reference range for changes in the transcriptome, metabolome and proteome in various age groups and in various acute and chronic diseases<br>4. Correlation of systems biology data with disease activities of rare diseases<br>5. Specification of phenotyping of patients within different disease groups