Evaluation of surgical joint reconstructive procedure for treatment of patients with long-standing rheumatoid arthritis

Not Applicable

• Conditions: Rheumatoid Arthritis

• Registration Number: JPRN-UMIN000012649
• Lead Sponsor: agoya University Hospital

Brief Summary

1. Kojima T, Ishikawa H, Tanaka S, Haga N, Nishida K, Yukioka M, Hashimoto J, Miyahara H, Niki Y, Kimura T, Oda H, Asai S, Funahashi K, Kojima M, Ishiguro N. Characteristics of functional impairment in patients with long-standing rheumatoid arthritis based on range of motion of joints: Baseline data from a multicenter prospective observational cohort study to evaluate the effectiveness of joint surgery in the treat-to-target era. Mod Rheumatol. 2018;28(3):474-81. 2. Kojima T, Ishikawa H, Tanaka S, Haga N, Nishida K, Yukioka M, Hashimoto J, Miyahara H, Niki Y, Kimura T, Oda H, Asai S, Funahashi K, Kojima M, Ishiguro N. Validation and reliability of the Timed Up and Go test for measuring objective functional impairment in patients with long-standing rheumatoid arthritis: a cross-sectional study. Int J Rheum Dis. 2018;21(10):1793-800. 3. Kojima T, Ishikawa H, Tanaka S, Haga N, Nishida K, Yukioka M, Hashimoto J, Miyahara H, Niki Y, Kimura T, Oda H, Asai S, Funahashi K, Kojima M, Ishiguro N. Target setting for lower limb joint surgery using the Timed Up and Go test in patients with rheumatoid arthritis: A prospective cohort study. Int J Rheum Dis. 2018;21(10):1801-8.

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2013-12-24
• Study Completion: 2014-12-31
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Complete: follow-up complete
• Sex: All
• Target Recruitment: 1000

Inclusion Criteria

Not provided

Exclusion Criteria

Patients 1)who have other diseases than rheumatoid arthritis which remarkable impacts on outcome measurement of this study 2)who cannot answer the questionnaires by themselves. (In case the patients who cannot answer them only by physical disability, have someone to support them, they can participate the study.) 3)who are considered not to fit to participate this study by physician.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Improvement of 1)physical function of daily life(HAQ-DI, DASH, lower limbs function),2) QOL(EQ-5D), and 3)depression severity by joint reconstructive surgery

Secondary Outcome Measures

Name	Time	Method
Baseline evaluation 1)Disability of long-standing RA patients who required joint reconstructive surgery 2)Relationship between range of motion of each joint and disability of daily life