The predictive value of FDG-PET-CT early during (chemo-)radiotherapy for local control of advanced stage head and neck cancer

Recruiting

• Conditions: 10027655; head and neck cancer; head and neck squamous cell carcinoma

• Registration Number: NL-OMON32415
• Lead Sponsor: Vrije Universiteit Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 13 May 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 20

Inclusion Criteria

patients with resectable advanced (stage III and IV) HNSCC scheduled for primary non-surgical treatment (radiotherapy with or without chemotherapy) with curative intent.

Exclusion Criteria

technically inoperable tumor

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Diagnostic accuracy of FDG-PET-CT applied 2 weeks after the start of primary<br /><br>radiotherapy (with or without chemotherapy) for resectable HNSCC to predict<br /><br>local failure in the primary and cervical node metastases.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>* FDG uptake level pretreatment<br /><br>* Residual FDG uptake level after 14 days of therapy<br /><br>* Change of FDG uptake<br /><br>.</p><br>