Brain stimulation in altering developmental factors in schizophrenia
Not Applicable
- Conditions
- Health Condition 1: null- Schizophrenia
- Registration Number
- CTRI/2014/12/005280
- Lead Sponsor
- Department of Biotechnology Ministry of Science and Technology under INCRE Fellowship
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 60
Inclusion Criteria
1.Diagnosis of Schizophrenia (F20.0-F20.9) according to ICD-10-DCR
2.Patients on a stable dose of antipsychotic medication
3.Patients of either sex aged between 18-60 years.
4.Right handed, normotensive patients.
5.Patients giving written informed consent.
6.Screened eligible for rTMS.
Exclusion Criteria
1.Current neurological or any comorbid psychiatric disorders.
2.History of substance abuse (Except nicotine and caffeine) in the past one month.
3.History of epilepsy, significant head injury or any neurosurgical procedure.
4.Subjects with cardiac pacemakers or other metal parts in the body.
5.Subjects who have received ECT in past 6 months.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Schneiderian First rank symptoms (FRS) assessed with a specially designed score sheetTimepoint: Baseline and at the end of 2 weeks of rTMS treatment
- Secondary Outcome Measures
Name Time Method high resolution gamma oscillatory activity, BDNF levels, self monitoring task and overall psychopathology scores on PANSSTimepoint: Baseline and at the end of 2 weeks of rTMS treatment