TCTR20240514001已完成3 期
Effect of vaginal estradiol 10 micrograms on vaginal microbiome in women with genitourinary syndrome of menopause : A Randomized Controlled Trial
Ratchadapiseksompotch Fund, Chulalongkorn University0 个研究点目标入组 40 人开始时间: 2024年5月14日最近更新:
适应症
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 发起方
- 入组人数
- 40
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 45 Years 至 70 Years（—）
- 性别
- Female
入选标准
- •1. Two or more years since last natural menstrual period, or surgical menopause (bilateral oophorectomy)
- •2. Moderate to severe genitourinary symptoms ( at least one symptom of burning, dryness, itching, irritation, soreness and/or bleeding, dyspareunia)
- •3. Follicle stimulating hormone (FSH) concentrations more than 40 IU/L
- •4. Serum estradiol concentrations 20 pg/mL or less
排除标准
- •1. Previous hormone therapy in the past 3 months
- •2. Current use of a vaginal pessary, urinary tract infection
- •3. Antibiotic exposure or vaginal medications in the past 30 days
- •Any contraindications to estrogen
- •4. Systemic diseases or chronic conditions (diabetes mellitus, immunological disease), use of immuno suppressive drugs, exogenous corticosteroids, chemotherapy
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