NCT01089257终止不适用
Subclinical Cardiovascular Impairments in Patients With Obstructive Sleep Apnea Syndrome
University Hospital, Grenoble2 个研究点 分布在 1 个国家目标入组 133 人开始时间: 2007年11月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 发起方
- 入组人数
- 133
- 试验地点
- 2
研究概览
简要总结
Which are the anthropometric parameters and/or of severity of the syndrome of apnea of sleep (SAS) which make it possible to anticipate occurred of vascular anomalies, anatomical and/or functional precociously found among patients SAS? Secondary objectives:
- Which are the anthropometric parameters and/or of severity of SAS allowing to anticipate occurred of early of the cardiac function and/or rhythmic anomalies found among patients SAS?
- Do there exist biological markers who allow to anticipate the early vascular lesions or the anomalies beginners of the cardiac function?
- Which are the cardiovascular effects of a treatment of SAS by Continuous Positive Pressure (PC) after 3 to 6 months of treatment?
- Do the identified early cardiovascular attacks and/or the biological anomalies make it possible to predict occurred of cardiovascular events in this population of patients carrying SAS (followed longitudinal at 5 years)?
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 78 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Male or female from 18 to 78 years old
- •Patients with obstructive sleep apnea syndrome (Apnea/Hypopnea index > 15)
- •ambulatory patients
- •patients who have signed the inform consent form
- •patients with health insurance
排除标准
- •Body Mass Index upper or equal to 30
- •cardiovascular pathology except blood pressure hypertension
- •known or treated diabetes
- •pathologies with consequence on blood pressure regulation
- •drugs intakes with consequence on blood pressure regulation
- •patient with chronic obstructive pulmonary disease
- •atrial fibrillation or more than 10/minute extrasystoles
- •bedridden patients or patients with decreased mobility
- •patients working at night or with shift work
- •patients with carotid stenting or surgery history
- •patients unable to sign the inform consent form
- •patients already treated by cPAP or dental appliance for OSAS in the last 6 months
- •pregnant or suckling female
- •patients under supervision or trusteeship
- •patients taking part in another clinical trial
研究者
研究点 (2)
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