The Effects of Four Commonly Consumed Seeds (Flax, Poppy, Sesame & Salba) on Postprandial Blood Glucose Response, Vascular, Appetite and Sensory Parameters in Healthy Individuals
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 入组人数
- 21
- 试验地点
- 2
- 主要终点
- Postprandial Blood Glucose
研究概览
简要总结
Consumption of whole grains has been heavily endorsed by both government and major health agencies, as evidenced in Health Canada's Food Guide, the US Department of Agriculture's Food Pyramid, and the Heart and Stroke Foundation's healthy eating guide. Whole grains have been championed for their proposed cardioprotective and weight control effects as suggested by epidemiological studies. The health benefits of whole grain products may be attributable to their nutrient composition, which contains dietary fibre, protein and several essential nutrients. There has also been a concurrent increase in seed consumption. Seeds have a similar and potentially superior nutritional composition to whole grains and they are rich in mammalian lignans and polyunsaturated fats, especially the highly valued omega-3 fatty acids. Preliminary studies on seeds have shown that they impart health benefits similar to those imparted by whole grains. Consumer choices regarding seed consumption may be based on their potential health benefits. Furthermore, they may also be affected by subjective sensory factors, such as appearance, taste and pre-conceived perceptions. Therefore, this study will compare the health properties of four seeds and their effects on appetite and sensory parameters in healthy individuals. These four seeds will be that of flax, poppy and sesame, due to their popularity and consumption as well as Salba, which has also recently received much attention for its associated health benefits.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Prevention
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 65 Years(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •age 18-65 years
- •normal glycemic response
- •BMI between 18.5 - 25 kg/m2
- •peripheral systolic and diastolic blood pressure < 140mmHg and < 90mmHg
排除标准
- •known history of liver or kidney disease, diabetes, hypertension, stroke or myocardial infarctions, thyroid disease, Celiac disease/gastrointestinal disease, or AIDS;
- •allergies to any of the test products
- •using prescription medications or Natural Health Products
- •any condition which, in the opinion of the investigator, might jeopardize the health and safety of the subject or study personnel, or adversely affect the study results
研究组 & 干预措施
Flaxseed
25g of ground flaxseed baked into a bran muffin
干预措施: Flaxseed (Dietary Supplement)
Salba
25g of ground Salba baked into a bran muffin
干预措施: Salba (Dietary Supplement)
Poppy
25g of ground poppy seeds baked into a bran muffin
干预措施: Poppy (Dietary Supplement)
Sesame
25g of ground sesame seeds baked into a bran muffin
干预措施: Sesame (Dietary Supplement)
结局指标
主要结局
Postprandial Blood Glucose
时间窗: 3 hours
At each visit, postprandial blood glucose will be measured every 15 minutes over 3 hours.
次要结局
- Arterial Stiffness(3 hours)
- Personal Preference(3 hours)
- Blood Pressure(3 hours)
- Palatability(3 hours)
- Satiety(3 hours)
研究者
Vladimir Vuksan
Dr. Vladimir Vuksan
Unity Health Toronto
